Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8700175 | 0.88 | KDM4E (0.36) | ALDH1A1NPSR1 | |
| SCHEMBL8705376 | 0.87 | KDM4E (0.40) | ALDH1A1MAPTNPSR1 | |
| SCHEMBL8706344 | 0.86 | SYK (0.39) | ALDH1A1 | |
| SCHEMBL8700058 | 0.82 | SLC9A1 (0.48) | — | |
| SCHEMBL8701409 | 0.81 | MAPT (0.40) | ALDH1A1MAPTNPSR1 | |
| SCHEMBL9179571 | 0.76 | DRD2 (0.45) | — | |
| SCHEMBL8704819 | 0.75 | BTK (0.39) | ALDH1A1NPSR1 | |
| SCHEMBL31262548 | 0.74 | OPRK1 (0.43) | — | |
| SCHEMBL8705825 | 0.73 | KDM4E (0.48) | ALDH1A1NPSR1L3MBTL1 | |
| SCHEMBL8703772 | 0.72 | KDM4E (0.37) | ALDH1A1NPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5753680-A | Heterocyclyl-benzoylguanidines | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1998-05-19 | — | — | US | disclosed |