Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 3/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.53 |
| ▸ | USP2 | O75604 | 1/20 | 0.53 |
| ▸ | LMNA | P02545 | 1/20 | 0.53 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.53 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.53 |
| ▸ | FAAH | O00519 | 14/20 | 0.53 |
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8699709 | 0.91 | FAAH (0.57) | KDM4EALDH1A1FAAH | |
| SCHEMBL8699451 | 0.90 | FAAH (0.51) | MAPK1KDM4EALDH1A1FAAH | |
| SCHEMBL9057732 | 0.88 | FAAH (0.54) | MAPK1KDM4EALDH1A1LMNAALOX15 | |
| SCHEMBL8704931 | 0.86 | RBP4 (0.57) | MAPK1KDM4EALDH1A1USP2LMNA | |
| SCHEMBL8704718 | 0.84 | FAAH (0.49) | MAPK1KDM4EALDH1A1LMNAALOX15 | |
| SCHEMBL8700940 | 0.83 | RBP4 (0.61) | MAPK1KDM4EALDH1A1LMNAMEN1 | |
| SCHEMBL8703773 | 0.82 | RBP4 (0.51) | MAPK1KDM4EALDH1A1USP2LMNA | |
| SCHEMBL8705064 | 0.82 | HTR1A (0.52) | MAPK1KDM4EALDH1A1USP2LMNA | |
| SCHEMBL8705983 | 0.81 | MAPT (0.57) | MAPK1KDM4EALDH1A1USP2HSD17B10 | |
| SCHEMBL8699402 | 0.81 | KMT2A (0.49) | MAPK1KDM4EALDH1A1USP2LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5780472-A | ANTITUMOR AGENTS | SAMJIN PHARMACEUTICAZL CO., LTD. (KR) | 1998-07-14 | — | — | US | disclosed |
| EP-0749425-A1 | NEW PIPERAZINE DERIVATIVES AND METHODS FOR THE PREPARATION THEREOF AND COMPOSITIONS CONTAINING THE SAME | SAMJIN PHARM. CO., LTD. (KR) | 1996-12-27 | — | — | EP | disclosed |
| WO-1996021648-A1 | NEW PIPERAZINE DERIVATIVES AND METHODS FOR THE PREPARATION THEREOF AND COMPOSITIONS CONTAINING THE SAME | SAMJIN PHARMACEUTICAL CO., LTD. (KR) | 1996-07-18 | — | — | WO | disclosed |