Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FAAH | O00519 | 12/20 | 0.57 |
| ▸ | PHGDH | O43175 | 1/20 | 0.49 |
| ▸ | PRKAB2 | O43741 | 2/20 | 0.48 |
| ▸ | PRKAG1 | P54619 | 2/20 | 0.48 |
| ▸ | PRKAA2 | P54646 | 2/20 | 0.48 |
| ▸ | PRKAA1 | Q13131 | 2/20 | 0.48 |
| ▸ | PRKAG3 | Q9UGI9 | 2/20 | 0.48 |
| ▸ | PRKAG2 | Q9UGJ0 | 2/20 | 0.48 |
| ▸ | PRKAB1 | Q9Y478 | 2/20 | 0.48 |
| ▸ | POLB | P06746 | 2/20 | 0.47 |
| ▸ | PKM | P14618 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8699451 | 0.91 | FAAH (0.51) | FAAHPHGDHKDM4EALDH1A1 | |
| SCHEMBL8700472 | 0.91 | MAPK1 (0.53) | FAAHKDM4EALDH1A1 | |
| SCHEMBL8703304 | 0.86 | MAPT (0.55) | PHGDHALDH1A1 | |
| SCHEMBL9057732 | 0.83 | FAAH (0.54) | FAAHPHGDHPKMKDM4EALDH1A1 | |
| SCHEMBL9057828 | 0.83 | MAPT (0.53) | ALDH1A1 | |
| SCHEMBL6960671 | 0.83 | KMT2A (0.47) | PHGDHPOLBKDM4EALDH1A1 | |
| SCHEMBL8701376 | 0.82 | RBP4 (0.48) | KDM4EALDH1A1 | |
| SCHEMBL8701048 | 0.82 | THRB (0.47) | POLBALDH1A1 | |
| SCHEMBL8702748 | 0.81 | RBP4 (0.45) | POLBKDM4EALDH1A1 | |
| SCHEMBL8703751 | 0.80 | MAPT (0.48) | ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5780472-A | ANTITUMOR AGENTS | SAMJIN PHARMACEUTICAZL CO., LTD. (KR) | 1998-07-14 | — | — | US | disclosed |
| EP-0749425-A1 | NEW PIPERAZINE DERIVATIVES AND METHODS FOR THE PREPARATION THEREOF AND COMPOSITIONS CONTAINING THE SAME | SAMJIN PHARM. CO., LTD. (KR) | 1996-12-27 | — | — | EP | disclosed |
| WO-1996021648-A1 | NEW PIPERAZINE DERIVATIVES AND METHODS FOR THE PREPARATION THEREOF AND COMPOSITIONS CONTAINING THE SAME | SAMJIN PHARMACEUTICAL CO., LTD. (KR) | 1996-07-18 | — | — | WO | disclosed |