Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PKM | P14618 | 1/20 | 0.42 |
| ▸ | ADORA2B | P29275 | 4/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | BRD4 | O60885 | 3/20 | 0.39 |
| ▸ | MAPT | P10636 | 3/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.39 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.39 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.39 |
| ▸ | CACNA1D | Q01668 | 1/20 | 0.39 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7421543 | 0.76 | OPRM1 (0.47) | BRD4SLC6A4HSD17B10 | |
| SCHEMBL4021580 | 0.72 | SLC6A2 (0.43) | PKMADORA2BALDH1A1KMT2ABRD4 | |
| SCHEMBL8700638 | 0.71 | HTT (0.52) | PKMADORA2BALDH1A1KMT2ABRD4 | |
| SCHEMBL8189527 | 0.70 | LMNA (0.41) | PKMALDH1A1BRD4SLC6A2SLC6A4 | |
| SCHEMBL11264454 | 0.69 | SLC6A2 (0.38) | PKMADORA2BALDH1A1KMT2ASLC6A2 | |
| SCHEMBL1428238 | 0.67 | OPRM1 (0.44) | ALDH1A1MAPTSLC6A4KDM4E | |
| SCHEMBL19419804 | 0.67 | BRD4 (0.46) | KMT2ABRD4SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL7415776 | 0.67 | CHRM3 (0.51) | SLC6A2SLC6A4TSHR | |
| SCHEMBL22640245 | 0.67 | HSD17B10 (0.44) | PKMADORA2BALDH1A1KMT2ABRD4 | |
| SCHEMBL244317 | 0.67 | OPRM1 (0.43) | PKMADORA2BALDH1A1KMT2AMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5789415-A | Azacyclic-heterocyclic compounds as angiotension II receptor antagonists | PFIZER INC. (US) | 1998-08-04 | — | — | US | disclosed |