Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A2 | P23975 | 7/20 | 0.38 |
| ▸ | SLC6A4 | P31645 | 7/20 | 0.38 |
| ▸ | PKM | P14618 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | ADORA2B | P29275 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | SLC22A1 | O15245 | 1/20 | 0.34 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4021580 | 0.77 | SLC6A2 (0.43) | SLC6A2SLC6A4PKMALDH1A1ADORA2B | |
| SCHEMBL8189527 | 0.74 | LMNA (0.41) | SLC6A2SLC6A4PKMALDH1A1KDM4E | |
| SCHEMBL244317 | 0.69 | OPRM1 (0.43) | SLC6A4PKMALDH1A1ADORA2BKMT2A | |
| SCHEMBL8700636 | 0.69 | PKM (0.42) | SLC6A2SLC6A4PKMALDH1A1ADORA2B | |
| SCHEMBL7421543 | 0.68 | OPRM1 (0.47) | SLC6A4LMNAHSD17B10SLC22A1SMN1; SMN2 | |
| SCHEMBL1428238 | 0.67 | OPRM1 (0.44) | SLC6A4ALDH1A1KDM4ELMNASLC22A1 | |
| SCHEMBL7415776 | 0.67 | CHRM3 (0.51) | SLC6A2SLC6A4LMNATSHRSLC22A1 | |
| SCHEMBL1428246 | 0.66 | CHRM3 (0.53) | SLC6A2SLC6A4LMNATSHRSLC22A1 | |
| SCHEMBL7414392 | 0.66 | CHRM3 (0.53) | SLC6A2SLC6A4LMNATSHRSLC22A1 | |
| SCHEMBL29513187 | 0.65 | ALDH1A1 (0.37) | SLC6A2SLC6A4PKMALDH1A1ADORA2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4360520-A | 1,4-Dihydropyridazine compounds, and their medicinal use | BAYER AKTIENGESELLSCHAFT (DE) | 1982-11-23 | — | — | US | disclosed |