Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.38 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | PKM | P14618 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8697759 | 0.78 | HRH3 (0.45) | HRH3SMN1; SMN2HSD17B10ALDH1A1KDM4E | |
| SCHEMBL9033194 | 0.78 | HRH3 (0.45) | HRH3SMN1; SMN2HSD17B10ALDH1A1KDM4E | |
| SCHEMBL9033398 | 0.77 | SLC6A3 (0.42) | ALDH1A1 | |
| SCHEMBL8177110 | 0.76 | HRH3 (0.55) | HRH3SMN1; SMN2HSD17B10ALDH1A1KDM4E | |
| SCHEMBL22916606 | 0.74 | RAB9A (0.56) | HSD17B10ALDH1A1KDM4EL3MBTL1MAPT | |
| SCHEMBL9033441 | 0.74 | HRH3 (0.43) | HRH3SMN1; SMN2HSD17B10ALDH1A1KDM4E | |
| SCHEMBL8702739 | 0.73 | HRH3 (0.45) | HRH3SMN1; SMN2ALDH1A1KDM4EL3MBTL1 | |
| SCHEMBL28046877 | 0.72 | L3MBTL1 (0.46) | HRH3HSD17B10ALDH1A1L3MBTL1MAPT | |
| SCHEMBL9033054 | 0.72 | HRH3 (0.44) | HRH3SMN1; SMN2HSD17B10ALDH1A1KDM4E | |
| SCHEMBL9032686 | 0.72 | HRH3 (0.41) | HRH3SMN1; SMN2HSD17B10ALDH1A1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5834460-A | FOR TREATMENT OF BRAIN OR PSYCHOLOGICAL DISORDERS, ALZHEIMER*S DISEASE, MENTAL RETARDATION OR AUTISM | YAMANOUCHI PHARMACEUTICAL CO., LTD. (JP) | 1998-11-10 | — | — | US | disclosed |
| EP-0696586-A1 | SERINE DERIVATIVE | YAMANOUCHI PHARMACEUTICAL CO. LTD. (JP) | 1996-02-14 | — | — | EP | disclosed |