Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FAAH | O00519 | 1/20 | 0.50 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.48 |
| ▸ | TBXAS1 | P24557 | 3/20 | 0.47 |
| ▸ | CPB1 | P15086 | 1/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | CACNA1G | O43497 | 1/20 | 0.47 |
| ▸ | CACNA1H | O95180 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8540312 | 0.94 | GRIN2B (0.55) | FAAHGRIN2BKDM4EALDH1A1TBXAS1 | |
| SCHEMBL8541116 | 0.89 | FAAH (0.57) | FAAHGRIN2BKDM4EALDH1A1TBXAS1 | |
| SCHEMBL8545335 | 0.87 | HDAC3 (0.54) | FAAHGRIN2BKDM4EALDH1A1TBXAS1 | |
| SCHEMBL9031024 | 0.84 | PKM (0.53) | FAAHGRIN2BKDM4EALDH1A1CPB1 | |
| SCHEMBL8540403 | 0.83 | TBXAS1 (0.46) | FAAHGRIN2BTBXAS1CPB1MEN1 | |
| SCHEMBL8545661 | 0.83 | GRIN2B (0.46) | FAAHGRIN2BALDH1A1TBXAS1CPB1 | |
| SCHEMBL8541801 | 0.82 | GRIN2B (0.57) | FAAHGRIN2BALDH1A1TBXAS1MEN1 | |
| SCHEMBL8538300 | 0.82 | GRIN2B (0.54) | GRIN2B | |
| SCHEMBL8546276 | 0.81 | CPB1 (0.55) | GRIN2BKDM4EALDH1A1CPB1MAPK1 | |
| Hydrochloric Acid SCHEMBL8546852 | 0.81 | GRIN2B (0.53) | GRIN2BTBXAS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0705258-B1 | AZOLYL-CYCLIC AMINE DERIVATIVES WITH IMMUNOMODULATORY ACTIVITY | KNOLL AG (DE) | 1998-12-30 | — | — | EP | disclosed |
| EP-0705258-A1 | AZOLYL-CYCLIC AMINE DERIVATIVES WITH IMMUNOMODULATORY ACTIVITY | Knoll AG (DE) | 1996-04-10 | — | — | EP | disclosed |
| WO-1995000507-A1 | AZOLYL-CYCLIC AMINE DERIVATIVES WITH IMMUNOMODULATORY ACTIVITY | KNOLL AG (DE) | 1995-01-05 | — | — | WO | disclosed |