Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.48 |
| ▸ | POLB | P06746 | 2/20 | 0.48 |
| ▸ | HPGD | P15428 | 1/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.48 |
| ▸ | AOC2 | O75106 | 4/20 | 0.42 |
| ▸ | F2 | P00734 | 4/20 | 0.36 |
| ▸ | F10 | P00742 | 4/20 | 0.36 |
| ▸ | PLAU | P00749 | 4/20 | 0.36 |
| ▸ | PLAT | P00750 | 4/20 | 0.36 |
| ▸ | RAB9A | P51151 | 3/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | DNMT1 | P26358 | 1/20 | 0.36 |
| ▸ | CASP6 | P55212 | 1/20 | 0.36 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | PPIA | P62937 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8705142 | 0.81 | ALDH1A1 (0.48) | ALDH1A1KDM4EPOLBHPGDMAPK1 | |
| SCHEMBL21884446 | 0.80 | KAT6A (0.43) | ALDH1A1KDM4EMAPK1MAPTGAA | |
| SCHEMBL8703970 | 0.80 | SIRT6 (0.41) | ALDH1A1KDM4EPOLBHPGDMAPK1 | |
| Hydrochloric Acid SCHEMBL8705159 | 0.79 | SIRT6 (0.40) | ALDH1A1KDM4EPOLBHPGDMAPK1 | |
| SCHEMBL8701429 | 0.77 | ALDH1A1 (0.45) | ALDH1A1KDM4EPOLBHPGDMAPK1 | |
| SCHEMBL8704862 | 0.77 | AOC2 (0.65) | ALDH1A1POLBHPGDAOC2RAB9A | |
| SCHEMBL8705516 | 0.77 | AOC2 (0.68) | ALDH1A1AOC2RAB9AL3MBTL1NPC1 | |
| Hydrochloric Acid SCHEMBL8707141 | 0.76 | AOC2 (0.63) | ALDH1A1POLBHPGDAOC2RAB9A | |
| Hydrochloric Acid SCHEMBL8700020 | 0.75 | AOC2 (0.66) | ALDH1A1AOC2RAB9AL3MBTL1NPC1 | |
| SCHEMBL130491 | 0.75 | KDM4E (0.74) | ALDH1A1KDM4EPOLBHPGDMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5824691-A | CARDIOVASCULAR, CEREBROVASCULAR, RENAL DISEASES; SHOCK, ARTERIOSCLEROSIS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1998-10-20 | — | — | US | disclosed |