Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 3/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | MRGPRX1 | Q96LB2 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | POLB | P06746 | 2/20 | 0.39 |
| ▸ | AOC2 | O75106 | 2/20 | 0.39 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.39 |
| ▸ | TUBB | P07437 | 1/20 | 0.39 |
| ▸ | TUBA3C | P0DPH7 | 1/20 | 0.39 |
| ▸ | TUBA1B | P68363 | 1/20 | 0.39 |
| ▸ | TUBA4A | P68366 | 1/20 | 0.39 |
| ▸ | TUBB4B | P68371 | 1/20 | 0.39 |
| ▸ | TUBB3 | Q13509 | 1/20 | 0.39 |
| ▸ | TUBB2A | Q13885 | 1/20 | 0.39 |
| ▸ | TUBB8 | Q3ZCM7 | 1/20 | 0.39 |
| ▸ | TUBA3E | Q6PEY2 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8701429 | 0.95 | ALDH1A1 (0.45) | ALDH1A1SMN1; SMN2L3MBTL1GAAKMT2A | |
| SCHEMBL8701419 | 0.81 | ALDH1A1 (0.48) | ALDH1A1L3MBTL1GAAMAPTKDM4E | |
| SCHEMBL7830164 | 0.79 | ALDH1A1 (0.49) | ALDH1A1SMN1; SMN2L3MBTL1GAAKMT2A | |
| SCHEMBL5323825 | 0.78 | ALDH1A1 (0.57) | ALDH1A1SMN1; SMN2MAPTKDM4EPOLB | |
| SCHEMBL8701432 | 0.77 | ALDH1A1 (0.42) | ALDH1A1SMN1; SMN2L3MBTL1GAAKMT2A | |
| SCHEMBL8706316 | 0.77 | ALDH1A1 (0.48) | ALDH1A1SMN1; SMN2L3MBTL1GAAKMT2A | |
| Guanidine SCHEMBL8701424 | 0.77 | ALDH1A1 (0.41) | ALDH1A1SMN1; SMN2L3MBTL1GAAKMT2A | |
| SCHEMBL7826071 | 0.76 | ALDH1A1 (0.44) | ALDH1A1SMN1; SMN2TUBB4ATUBBTUBA3C | |
| SCHEMBL8703970 | 0.76 | SIRT6 (0.41) | ALDH1A1SMN1; SMN2KMT2AMAPTKDM4E | |
| Hydrochloric Acid SCHEMBL8705159 | 0.75 | SIRT6 (0.40) | ALDH1A1SMN1; SMN2KMT2AMAPTKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5824691-A | CARDIOVASCULAR, CEREBROVASCULAR, RENAL DISEASES; SHOCK, ARTERIOSCLEROSIS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1998-10-20 | — | — | US | disclosed |