Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AGTR1 | P30556 | 1/20 | 0.42 |
| ▸ | AGTR2 | P50052 | 1/20 | 0.42 |
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8092915 | 0.89 | AGTR2 (0.48) | AGTR1AGTR2 | |
| SCHEMBL8088528 | 0.88 | — | — | |
| SCHEMBL8701616 | 0.87 | AGTR2 (0.54) | AGTR1AGTR2 | |
| SCHEMBL8708854 | 0.77 | AGTR1 (0.50) | AGTR1AGTR2 | |
| SCHEMBL8094878 | 0.76 | AGTR2 (0.58) | AGTR1AGTR2 | |
| SCHEMBL8088442 | 0.76 | AGTR2 (0.65) | AGTR1AGTR2 | |
| SCHEMBL8089466 | 0.75 | TLR7 (0.52) | AGTR1AGTR2TLR7 | |
| SCHEMBL8092916 | 0.74 | AGTR1 (0.45) | AGTR1AGTR2 | |
| SCHEMBL8092218 | 0.73 | AGTR2 (0.60) | AGTR1AGTR2 | |
| SCHEMBL8089387 | 0.72 | AGTR2 (0.62) | AGTR1AGTR2TLR7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5798364-A | ANGIOTENSIN II ANTAGONIST, USEFUL FOR TREATMENT OF HYPERTENSION, ALDOSTERONISM AND CARDIAC INSUFFICIENCY | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1998-08-25 | — | — | US | disclosed |