Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP19A1 | P11511 | 7/20 | 0.41 |
| ▸ | ATM | Q13315 | 1/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | CASP1 | P29466 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 3/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.33 |
| ▸ | CCNC | P24863 | 1/20 | 0.33 |
| ▸ | CDK8 | P49336 | 1/20 | 0.33 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.33 |
| ▸ | CYP2E1 | P05181 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8697579 | 0.92 | CYP19A1 (0.51) | CYP19A1ATMALOX15TSHRCASP1 | |
| SCHEMBL8699069 | 0.91 | CYP19A1 (0.57) | CYP19A1RAB9ANPC1CYP3A4 | |
| SCHEMBL8697882 | 0.91 | CYP19A1 (0.40) | CYP19A1ATMALOX15TSHRCASP1 | |
| SCHEMBL8698474 | 0.87 | CYP19A1 (0.38) | CYP19A1RAB9ANPC1CYP3A4 | |
| SCHEMBL8698611 | 0.82 | CYP19A1 (0.41) | CYP19A1ATMCCNCCDK8CYP3A4 | |
| SCHEMBL8698102 | 0.79 | CYP19A1 (0.51) | CYP19A1ATMALOX15TSHRCASP1 | |
| SCHEMBL8697944 | 0.78 | CYP3A4 (0.43) | CYP19A1TSHRCYP3A4CYP2D6CYP2C19 | |
| SCHEMBL8700748 | 0.77 | CYP3A4 (0.36) | CYP19A1TSHRCYP3A4CYP2D6CYP2C19 | |
| SCHEMBL8702833 | 0.74 | CYP19A1 (0.57) | CYP19A1RAB9ACYP3A4 | |
| SCHEMBL8700104 | 0.74 | CYP19A1 (0.45) | CYP19A1ATMTSHRKDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1998018791-A1 | HETEROCYCLIC FURAN COMPOUNDS, THEIR PREPARATION AND USE AS AROMATASE INHIBITORS | A. MENARINI INDUSTRIE FARMACEUTICHE RIUNITE S.R.L. (IT) | 1998-05-07 | — | — | WO | disclosed |