SCHEMBL8704686

SCHEMBL8704686

[O]c1ccc2ccccc2c1Oc1ccc2ccccc2c1

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ENPP3 O14638 1/20 0.44
ALPL P05186 1/20 0.44
ENPP1 P22413 1/20 0.44
XIAP P98170 1/20 0.44
GAA P10253 2/20 0.43
RCE1 Q9Y256 1/20 0.43
HAO1 Q9UJM8 1/20 0.42
MAOA P21397 1/20 0.42
MAOB P27338 1/20 0.42
CYP1A2 P05177 2/20 0.42
CYP2A6 P11509 2/20 0.42
MAPT P10636 5/20 0.42
ALDH1A1 P00352 4/20 0.42
HTT P42858 3/20 0.42
KDM4E B2RXH2 3/20 0.42
HPGD P15428 2/20 0.42
MEN1 O00255 2/20 0.42
KMT2A Q03164 2/20 0.42
GLA P06280 1/20 0.42
THRB P10828 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL676532 0.85 MAPT (0.50) CYP2A6MAPTALDH1A1HTTKDM4E
SCHEMBL30006655 0.80 GAA (0.49) ENPP3ALPLENPP1XIAPGAA
SCHEMBL6784168 0.79 NPBWR1 (0.49) CYP1A2MAPTALDH1A1HTTKDM4E
SCHEMBL21821223 0.79 PTPN22 (0.47) ENPP3ALPLENPP1XIAPGAA
SCHEMBL18162301 0.76 PIN1 (0.51) ENPP3ALPLENPP1XIAPMAPT
SCHEMBL395026 0.73 CYP1A2 (0.64) ENPP3ALPLENPP1XIAPGAA
SCHEMBL29366638 0.73 CYP1A2 (0.64) ENPP3ALPLENPP1XIAPGAA
SCHEMBL1402567 0.73 ALDH1A1 (0.50) CYP2A6MAPTALDH1A1KDM4EHPGD
SCHEMBL16920393 0.73 ENPP3 (0.53) ENPP3ALPLENPP1XIAPGAA
SCHEMBL30731587 0.72 GAA (0.61) GAARCE1HAO1MAOAMAOB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5705453-A INSECTICIDES, MITICIDES, FUNGICIDES MITSUBISHI CHEMICAL CORPORATION (JP) 1998-01-06 US disclosed