Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.50 |
| ▸ | GLA | P06280 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.50 |
| ▸ | PGR | P06401 | 2/20 | 0.43 |
| ▸ | TSHR | P16473 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | LTA4H | P09960 | 1/20 | 0.41 |
| ▸ | KDM1A | O60341 | 1/20 | 0.40 |
| ▸ | HPRT1 | P00492 | 1/20 | 0.38 |
| ▸ | ATM | Q13315 | 1/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.36 |
| ▸ | WDR5 | P61964 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | KCNA3 | P22001 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8704686 | 0.85 | ENPP3 (0.44) | MAPTKDM4EGLAKMT2ATSHR | |
| SCHEMBL6784168 | 0.82 | NPBWR1 (0.49) | MAPTKDM4EGLAKMT2APGR | |
| SCHEMBL1052575 | 0.78 | MAPT (0.52) | MAPTKDM4EGLAKMT2ATSHR | |
| SCHEMBL5992678 | 0.77 | KDM4E (0.50) | MAPTKDM4EGLAKMT2ATSHR | |
| SCHEMBL10627973 | 0.77 | KDM4E (0.46) | MAPTKDM4EGLAKMT2AALDH1A1 | |
| SCHEMBL1402567 | 0.76 | ALDH1A1 (0.50) | MAPTKDM4EKMT2ATSHRALDH1A1 | |
| SCHEMBL18650747 | 0.76 | MAPT (0.58) | MAPTKDM4EGLAKMT2APGR | |
| SCHEMBL28627795 | 0.75 | KDM4E (0.63) | MAPTKDM4EGLAKMT2ATSHR | |
| SCHEMBL19894095 | 0.74 | MAPT (0.61) | MAPTKDM4EGLAKMT2AALDH1A1 | |
| SCHEMBL2242408 | 0.73 | MAPT (0.46) | MAPTKDM4EGLAKMT2APGR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1645430-B1 | METHOD FOR PRODUCING MATERIAL CONTAINING SENSITIZER DISPERSED THEREIN FOR HEAT-SENSITIVE RECORDING MATERIAL | SANKO CO LTD (JP) | 2011-11-30 | — | — | EP | disclosed |
| US-20110274651-A1 | Noscapine and Noscapine Analogs and Their Use in treating Infectious Diseases by Tubulin Binding Inhibition | EMORY UNIVERSITY (US) | 2011-11-10 | — | — | US | disclosed |
| EP-2328578-A2 | NOSCAPINE AND NOSCAPINE ANALOGS AND THEIR USE IN TREATING INFECTIOUS DISEASES BY TUBULIN BINDING INHIBITION | Emory University (US) | 2011-06-08 | — | — | EP | disclosed |
| WO-2010030582-A2 | NOSCAPINE AND NOSCAPINE ANALOGS AND THEIR USE IN TREATING INFECTIOUS DISEASES BY TUBULIN BINDING INHIBITION | EMORY UNIVERSITY (US) | 2010-03-18 | — | — | WO | disclosed |
| US-20090233246-A1 | METHOD FOR PRODUCING MATERIAL CONTAINING SENSITIZER DISPERSED THEREIN FOR THERMAL RECORDING ARTICLE AND THERMAL RECORDING ARTICLE | ODA SHIGERU | 2009-09-17 | — | — | US | disclosed |
| US-7557065-B2 | Method for producing material containing sensitizer dispersed therein for thermal recording article and a thermal recording article | SANKO CO., LTD. (JP) | 2009-07-07 | — | — | US | disclosed |
| US-20060252645-A1 | Method for producing material containing sensitizer dispersed therein for thermal recording article an thermal recording article | SANKO CO., LTD. (JP) | 2006-11-09 | — | — | US | disclosed |
| EP-1645430-A1 | METHOD FOR PRODUCING MATERIAL CONTAINING SENSITIZER DISPERSED THEREIN FOR THERMAL RECORDING ARTICLE AND THERMAL RECORDING ARTICLE | Sanko Co., Ltd. (JP) | 2006-04-12 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110274651-A1 | Noscapine and Noscapine Analogs and Their Use in treating Infectious Diseases by Tubulin Binding Inhibition | NOS1, NOS2, TBCA | MAPT 28/4885KDM4E 4136/4885GLA 3901/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.