Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP4F2 | P78329 | 1/20 | 0.37 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.37 |
| ▸ | TAAR1 | Q96RJ0 | 4/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.36 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.36 |
| ▸ | P2RY12 | Q9H244 | 1/20 | 0.36 |
| ▸ | TBXAS1 | P24557 | 2/20 | 0.36 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.34 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.34 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.33 |
| ▸ | HTR1A | P08908 | 1/20 | 0.33 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.33 |
| ▸ | SYK | P43405 | 2/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
| ▸ | CYP4Z1 | Q86W10 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8304739 | 0.87 | TBXAS1 (0.46) | CYP4F2CYP4A11TAAR1MAPTPDE3B | |
| SCHEMBL8308082 | 0.83 | CYP4F2 (0.41) | CYP4F2CYP4A11TAAR1MAPTPDE3B | |
| SCHEMBL8707667 | 0.81 | CYP4F2 (0.42) | CYP4F2CYP4A11MAPTPDE3BPDE3A | |
| SCHEMBL11487887 | 0.80 | TAAR1 (0.48) | CYP4F2CYP4A11TAAR1MAPTPDE3B | |
| SCHEMBL11474938 | 0.79 | CYP4F2 (0.56) | CYP4F2CYP4A11TAAR1MAPTPDE3B | |
| SCHEMBL8702346 | 0.78 | TBXAS1 (0.49) | TBXAS1 | |
| SCHEMBL3591993 | 0.76 | MAPT (0.52) | CYP4F2CYP4A11TAAR1MAPTPDE3B | |
| SCHEMBL8304916 | 0.76 | PDE3B (0.36) | CYP4F2CYP4A11MAPTPDE3BPDE3A | |
| SCHEMBL8705232 | 0.74 | TBXAS1 (0.46) | TBXAS1ALDH1A1 | |
| SCHEMBL11475112 | 0.73 | ALOX5 (0.51) | CYP4F2CYP4A11TAAR1MAPTALOX5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5705523-A | THROMBOXANE A2 SYNTHETASE INHIBITORS | PFIZER INC. (US) | 1998-01-06 | — | — | US | disclosed |