Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.35 |
| ▸ | MCOLN3 | Q8TDD5 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.34 |
| ▸ | JAK2 | O60674 | 1/20 | 0.33 |
| ▸ | JAK1 | P23458 | 1/20 | 0.33 |
| ▸ | JAK3 | P52333 | 1/20 | 0.33 |
| ▸ | TRPM8 | Q7Z2W7 | 4/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.33 |
| ▸ | HTT | P42858 | 2/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | CRHR1 | P34998 | 1/20 | 0.32 |
| ▸ | BRD4 | O60885 | 1/20 | 0.32 |
| ▸ | BRD2 | P25440 | 1/20 | 0.32 |
| ▸ | BRD3 | Q15059 | 1/20 | 0.32 |
| ▸ | MAOA | P21397 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 4/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8705045 | 0.90 | MEN1 (0.35) | TSHRMCOLN3ALDH1A1JAK2JAK1 | |
| SCHEMBL9035643 | 0.89 | ALDH1A1 (0.33) | TSHRMCOLN3ALDH1A1JAK2JAK1 | |
| SCHEMBL8417992 | 0.87 | JAK2 (0.36) | TSHRMCOLN3ALDH1A1JAK2JAK1 | |
| SCHEMBL8705608 | 0.81 | JAK3 (0.33) | JAK2JAK1JAK3 | |
| SCHEMBL8416637 | 0.80 | MEN1 (0.36) | TSHRMCOLN3ALDH1A1JAK2JAK1 | |
| SCHEMBL9033105 | 0.79 | TRPM8 (0.31) | ALDH1A1TRPM8CRHR1MEN1KMT2A | |
| SCHEMBL9034137 | 0.79 | JAK2 (0.39) | TSHRMCOLN3ALDH1A1JAK2JAK1 | |
| Hydrochloric Acid SCHEMBL8708616 | 0.78 | MAOA (0.40) | TSHRMCOLN3ALDH1A1JAK2JAK1 | |
| SCHEMBL8840396 | 0.77 | MEN1 (0.33) | JAK2JAK1JAK3SMN1; SMN2MEN1 | |
| Hydrochloric Acid SCHEMBL8415221 | 0.76 | TRPM8 (0.35) | TSHRMCOLN3ALDH1A1JAK2JAK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5723450-A | Substituted pyridines, their preparation, and their use as pesticides and fungicides | HOECHST SCHERING AGREVO GMBH (DE) | 1998-03-03 | — | — | US | disclosed |