Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | CA12 | O43570 | 1/20 | 0.37 |
| ▸ | CA1 | P00915 | 1/20 | 0.37 |
| ▸ | CA2 | P00918 | 1/20 | 0.37 |
| ▸ | CA9 | Q16790 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8700353 | 0.86 | EED (0.42) | MAPTKDM4ENPC1ALDH1A1HPGD | |
| SCHEMBL9179571 | 0.83 | DRD2 (0.45) | CA12CA1CA2CA9 | |
| SCHEMBL7823474 | 0.82 | — | — | |
| SCHEMBL8705336 | 0.81 | ALDH1A1 (0.37) | MAPTALDH1A1NPSR1 | |
| Hydrochloric Acid SCHEMBL7835986 | 0.81 | — | — | |
| SCHEMBL9179580 | 0.77 | STS (0.39) | MAPTNPSR1CA12CA1CA2 | |
| SCHEMBL8575467 | 0.74 | MAPT (0.53) | MAPTALDH1A1NPSR1CA12CA1 | |
| SCHEMBL7835065 | 0.73 | SLC9A1 (0.48) | — | |
| SCHEMBL8700566 | 0.73 | KDM4E (0.55) | MAPTKDM4ENPC1ALDH1A1HPGD | |
| SCHEMBL8705825 | 0.73 | KDM4E (0.48) | KDM4ENPC1ALDH1A1RAB9ANPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5753680-A | Heterocyclyl-benzoylguanidines | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1998-05-19 | — | — | US | disclosed |