Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | ACHE | P22303 | 1/20 | 0.38 |
| ▸ | PDK2 | Q15119 | 3/20 | 0.37 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.37 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.37 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.37 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.37 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.37 |
| ▸ | GRIN2B | Q13224 | 2/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | CD44 | P16070 | 1/20 | 0.33 |
| ▸ | NQO2 | P16083 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.32 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.32 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.32 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.32 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.32 |
| ▸ | HSD11B2 | P80365 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4593445 | 0.69 | HDAC4 (0.34) | TSHRACHEHDAC4OPRM1OPRD1 | |
| SCHEMBL29060516 | 0.68 | OPRM1 (0.59) | TSHRACHEPDK2HDAC4OPRM1 | |
| SCHEMBL434296 | 0.67 | KMT2A (0.33) | TSHROPRM1OPRK1OPRL1ALDH1A1 | |
| SCHEMBL7313945 | 0.67 | PDK2 (0.46) | TSHRACHEPDK2HDAC4OPRM1 | |
| SCHEMBL28624389 | 0.65 | PDK2 (0.49) | TSHRACHEPDK2HDAC4OPRM1 | |
| SCHEMBL19743353 | 0.64 | PDK2 (0.43) | TSHRACHEPDK2GRIN2BCYP3A4 | |
| SCHEMBL17679906 | 0.64 | OPRM1 (0.46) | TSHRACHEPDK2HDAC4OPRM1 | |
| SCHEMBL8070982 | 0.64 | OPRM1 (0.46) | HDAC4OPRM1OPRD1OPRK1OPRL1 | |
| SCHEMBL5866512 | 0.64 | OPRM1 (0.46) | TSHRACHEPDK2HDAC4OPRM1 | |
| SCHEMBL5349864 | 0.64 | OPRM1 (0.54) | HDAC4OPRM1OPRD1OPRK1OPRL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1998039309-A1 | HETEROCYCLIC HERBICIDES | DUNLENA PTY. LIMITED (AU) | 1998-09-11 | — | — | WO | disclosed |