Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 2/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.37 |
| ▸ | TSHR | P16473 | 3/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.37 |
| ▸ | HTT | P42858 | 3/20 | 0.37 |
| ▸ | NPC1 | O15118 | 3/20 | 0.37 |
| ▸ | RAB9A | P51151 | 3/20 | 0.37 |
| ▸ | GLA | P06280 | 1/20 | 0.37 |
| ▸ | GRM1 | Q13255 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | CRHBP | P24387 | 1/20 | 0.35 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.35 |
| ▸ | JAK2 | O60674 | 1/20 | 0.35 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | PTGIR | P43119 | 1/20 | 0.34 |
| ▸ | MLYCD | O95822 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8699760 | 0.73 | ALDH1A1 (0.39) | POLBNPSR1ALDH1A1TSHRKMT2A | |
| M-Xylene SCHEMBL29227716 | 0.72 | RAB9A (0.50) | POLBNPSR1ALDH1A1TSHRKMT2A | |
| SCHEMBL1037096 | 0.72 | PTGIR (0.52) | POLBNPSR1ALDH1A1TSHRKMT2A | |
| SCHEMBL8700462 | 0.71 | GRM1 (0.40) | POLBNPSR1ALDH1A1TSHRHTT | |
| SCHEMBL7626374 | 0.71 | MEN1 (0.40) | POLBTSHRKMT2ANPC1RAB9A | |
| SCHEMBL19778 | 0.71 | NPSR1 (0.70) | POLBNPSR1ALDH1A1TSHRKMT2A | |
| SCHEMBL2092268 | 0.71 | RAB9A (0.53) | POLBNPSR1ALDH1A1TSHRKMT2A | |
| SCHEMBL19714098 | 0.70 | NPSR1 (0.40) | POLBNPSR1ALDH1A1TSHRKMT2A | |
| SCHEMBL8699064 | 0.70 | L3MBTL1 (0.39) | POLBNPSR1ALDH1A1TSHRKMT2A | |
| SCHEMBL5590843 | 0.69 | NPSR1 (0.47) | POLBNPSR1ALDH1A1TSHRKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5780472-A | ANTITUMOR AGENTS | SAMJIN PHARMACEUTICAZL CO., LTD. (KR) | 1998-07-14 | — | — | US | disclosed |
| EP-0749425-A1 | NEW PIPERAZINE DERIVATIVES AND METHODS FOR THE PREPARATION THEREOF AND COMPOSITIONS CONTAINING THE SAME | SAMJIN PHARM. CO., LTD. (KR) | 1996-12-27 | — | — | EP | disclosed |
| WO-1996021648-A1 | NEW PIPERAZINE DERIVATIVES AND METHODS FOR THE PREPARATION THEREOF AND COMPOSITIONS CONTAINING THE SAME | SAMJIN PHARMACEUTICAL CO., LTD. (KR) | 1996-07-18 | — | — | WO | disclosed |