Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CES2 | O00748 | 2/20 | 0.49 |
| ▸ | CES1 | P23141 | 2/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | ALPL | P05186 | 1/20 | 0.49 |
| ▸ | ALPI | P09923 | 1/20 | 0.49 |
| ▸ | ALPG | P10696 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.49 |
| ▸ | PLA2G4B | P0C869 | 9/20 | 0.48 |
| ▸ | PPARG | P37231 | 1/20 | 0.47 |
| ▸ | PPARA | Q07869 | 1/20 | 0.47 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | RECQL | P46063 | 1/20 | 0.46 |
| ▸ | PLA2G4A | P47712 | 1/20 | 0.46 |
| ▸ | FAAH | O00519 | 4/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8707397 | 0.81 | PLA2G4B (0.59) | MEN1ALPLALPIALPGKMT2A | |
| SCHEMBL9650471 | 0.81 | PLA2G4B (0.59) | MEN1ALPLALPIALPGKMT2A | |
| SCHEMBL1743419 | 0.80 | PLA2G4B (0.57) | MEN1ALPLALPIALPGKMT2A | |
| Dodecanoate SCHEMBL28099951 | 0.75 | PLA2G4B (0.68) | PLA2G4BPPARATSHRFAAH | |
| SCHEMBL6247942 | 0.74 | PLA2G4B (0.57) | MEN1ALPLALPIALPGKMT2A | |
| Pentane SCHEMBL8673099 | 0.74 | ALOX15 (0.77) | MEN1ALPLALPIALPGKMT2A | |
| Phenetole SCHEMBL11642283 | 0.74 | CES2 (0.49) | CES2CES1MEN1KMT2ATSHR | |
| SCHEMBL22208663 | 0.74 | DGKA (0.53) | CES2CES1TSHRFAAH | |
| SCHEMBL28097855 | 0.74 | DGKA (0.53) | CES2CES1TSHRFAAH | |
| SCHEMBL11644677 | 0.74 | LTA4H (0.60) | PLA2G4BTSHRFAAH |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0923567-A1 | BENZYLAMINE DERIVATIVES, THEIR PREPARATION AND THEIR APPLICATION IN THERAPEUTICS | SYNTHELABO (FR) | 1999-06-23 | — | — | EP | disclosed |
| WO-1998008834-A1 | BENZYLAMINE DERIVATIVES, THEIR PREPARATION AND THEIR APPLICATION IN THERAPEUTICS | SYNTHELABO (FR) | 1998-03-05 | — | — | WO | disclosed |