Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 7/20 | 0.55 |
| ▸ | MEN1 | O00255 | 5/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.54 |
| ▸ | POLB | P06746 | 2/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.51 |
| ▸ | TSHR | P16473 | 4/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.50 |
| ▸ | NPC1 | O15118 | 1/20 | 0.50 |
| ▸ | RAB9A | P51151 | 1/20 | 0.50 |
| ▸ | ERAP1 | Q9NZ08 | 1/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.46 |
| ▸ | GLA | P06280 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | CASP1 | P29466 | 1/20 | 0.46 |
| ▸ | CASP7 | P55210 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8706665 | 0.84 | KMT2A (0.57) | KMT2AMEN1KDM4EPOLBALDH1A1 | |
| SCHEMBL8708592 | 0.84 | KMT2A (0.64) | KMT2AMEN1KDM4EPOLBALDH1A1 | |
| Hydrochloric Acid SCHEMBL8702857 | 0.78 | KMT2A (0.52) | KMT2AMEN1KDM4EPOLBALDH1A1 | |
| Folescutol SCHEMBL554577 | 0.68 | TDP1 (0.81) | KMT2AMEN1KDM4EPOLBALDH1A1 | |
| SCHEMBL30507291 | 0.64 | ALDH1A1 (0.70) | KMT2AMEN1KDM4EPOLBALDH1A1 | |
| Oxazorone SCHEMBL2109280 | 0.64 | TDP1 (0.66) | KMT2AMEN1KDM4EPOLBALDH1A1 | |
| Oxazorone SCHEMBL29913823 | 0.64 | TDP1 (0.66) | KMT2AMEN1KDM4EPOLBALDH1A1 | |
| SCHEMBL15836699 | 0.63 | RAB9A (0.74) | KMT2AMEN1KDM4EPOLBALDH1A1 | |
| SCHEMBL24589796 | 0.62 | KMT2A (0.66) | KMT2AMEN1KDM4EPOLBALDH1A1 | |
| SCHEMBL466909 | 0.61 | CA12 (0.83) | KMT2AMEN1KDM4EPOLBALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0708766-B1 | USE OF COUMARINS AS PLA 2-INHIBITORS, NEW COUMARINS, PROCESS FOR PREPARING THE SAME AND MEDICAMENTS | BOEHRINGER MANNHEIM GMBH (DE) | 1997-12-10 | — | — | EP | disclosed |