Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.48 |
| ▸ | NAAA | Q02083 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | BLM | P54132 | 1/20 | 0.36 |
| ▸ | WRN | Q14191 | 1/20 | 0.36 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.36 |
| ▸ | DGKA | P23743 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 2/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | MGAM | O43451 | 1/20 | 0.33 |
| ▸ | SI | P14410 | 1/20 | 0.33 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | SOAT1 | P35610 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.31 |
| ▸ | DNM1 | Q05193 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL652060 | 0.82 | ALDH1A1 (0.54) | LMNAALDH1A1GAAHTTTSHR | |
| SCHEMBL17471938 | 0.82 | NAAA (0.45) | NAAAALDH1A1CYP1A2HPGDCYP2C19 | |
| SCHEMBL27630833 | 0.81 | NAAA (0.48) | LMNANAAAALDH1A1CYP1A2HPGD | |
| SCHEMBL8661878 | 0.79 | NAAA (0.47) | NAAAALDH1A1CYP1A2HPGDCYP2C19 | |
| SCHEMBL16897753 | 0.78 | NAAA (0.42) | LMNANAAAALDH1A1DGKAGAA | |
| SCHEMBL50301 | 0.78 | NAAA (0.64) | NAAAALDH1A1CYP1A2HPGDCYP2C19 | |
| SCHEMBL15416969 | 0.77 | LMNA (0.55) | LMNAALDH1A1DGKAGAAMGAM | |
| SCHEMBL450595 | 0.76 | NAAA (0.44) | LMNANAAAALDH1A1CYP1A2HPGD | |
| SCHEMBL472194 | 0.76 | TSHR (0.52) | LMNAALDH1A1HPGDHIF1ATSHR | |
| SCHEMBL15159057 | 0.76 | LMNA (0.43) | LMNAALDH1A1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1998018751-A1 | PRESENTATION OF BIOACTIVES | SCOTIA HOLDINGS PLC (GB) | 1998-05-07 | — | — | WO | disclosed |