Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NAAA | Q02083 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | DGKA | P23743 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | BLM | P54132 | 1/20 | 0.35 |
| ▸ | WRN | Q14191 | 1/20 | 0.35 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 2/20 | 0.32 |
| ▸ | DNM1 | Q05193 | 1/20 | 0.32 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.32 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7568718 | 0.87 | NAAA (0.61) | NAAAALDH1A1DGKAGAAHTT | |
| SCHEMBL8661878 | 0.84 | NAAA (0.47) | NAAAALDH1A1DGKAGAAHTT | |
| SCHEMBL17471938 | 0.83 | NAAA (0.45) | NAAAALDH1A1DGKAGAAHTT | |
| SCHEMBL27646117 | 0.83 | DGKA (0.50) | NAAAALDH1A1DGKABLMLMNA | |
| SCHEMBL50301 | 0.83 | NAAA (0.64) | NAAAALDH1A1DGKAGAAHTT | |
| SCHEMBL5918257 | 0.81 | NAAA (0.41) | NAAAALDH1A1GAAHTTCYP1A2 | |
| SCHEMBL8709489 | 0.81 | LMNA (0.48) | NAAAALDH1A1DGKAGAAHTT | |
| SCHEMBL25812326 | 0.80 | MMP1 (0.39) | ALDH1A1DGKA | |
| SCHEMBL8194855 | 0.80 | ALDH1A1 (0.38) | ALDH1A1DGKABLMADRA2AADRA1A | |
| Water SCHEMBL28123302 | 0.80 | NAAA (0.61) | NAAAALDH1A1DGKAGAAHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-100475810-C | Novel 2-arylthiazole compounds as pparalpha and ppargamma agonists | HOFFMANN LA ROCHE (CH) | 2009-04-08 | — | — | CN | disclosed |
| CN-1766733-A | Phototonus resin composition, spacer for display panel and display panel | JSR CORP (JP) | 2006-05-03 | — | — | CN | disclosed |
| CN-1678596-A | Novel 2-arylthiazole compounds as PPAR alpha and PPAR gamma agonists | HOFFMANN LA ROCHE (CH) | 2005-10-05 | — | — | CN | disclosed |