Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CSNK2A1 | P68400 | 3/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8713156 | 0.80 | PDE4A (0.33) | — | |
| SCHEMBL17625811 | 0.77 | LMNA (0.40) | — | |
| SCHEMBL8709749 | 0.76 | CSNK2A1 (0.41) | CSNK2A1 | |
| SCHEMBL2567613 | 0.74 | PRKDC (0.38) | — | |
| SCHEMBL18587679 | 0.73 | XDH (0.38) | — | |
| SCHEMBL15462234 | 0.71 | ACHE (0.36) | — | |
| SCHEMBL23214909 | 0.71 | TAAR1 (0.44) | CSNK2A1 | |
| SCHEMBL29768366 | 0.71 | TAAR1 (0.44) | CSNK2A1 | |
| SCHEMBL15463264 | 0.70 | APLNR (0.42) | — | |
| SCHEMBL2116744 | 0.70 | SLC6A4 (0.36) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5716971-A | FOR TREATMENT OF ANGINA PECTORIS AND HYPERTENSION | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1998-02-10 | — | — | US | disclosed |
| EP-0623597-B1 | Pyridine derivatives, with potassium channel opening activity | TAKEDA CHEMICAL INDUSTRIES LTD (JP) | 1997-10-22 | — | — | EP | disclosed |
| EP-0623597-A1 | Pyridine derivatives, with potassium channel opening activity | Takeda Chemical Industries, Ltd. (JP) | 1994-11-09 | — | — | EP | disclosed |