Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB3 | P05106 | 1/20 | 0.39 |
| ▸ | ITGAV | P06756 | 1/20 | 0.39 |
| ▸ | EGFR | P00533 | 1/20 | 0.38 |
| ▸ | ERBB2 | P04626 | 1/20 | 0.38 |
| ▸ | LARS1 | Q9P2J5 | 1/20 | 0.37 |
| ▸ | PPARA | Q07869 | 1/20 | 0.37 |
| ▸ | BCL2 | P10415 | 1/20 | 0.36 |
| ▸ | TARS1 | P26639 | 1/20 | 0.36 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 3/20 | 0.36 |
| ▸ | REN | P00797 | 1/20 | 0.36 |
| ▸ | SCN3A | Q9NY46 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 3/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.35 |
| ▸ | POLB | P06746 | 2/20 | 0.35 |
| ▸ | F2 | P00734 | 1/20 | 0.35 |
| ▸ | F10 | P00742 | 1/20 | 0.35 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 2/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8709961 | 0.93 | ITGB3 (0.36) | ITGB3ITGAVEGFRERBB2PPARA | |
| SCHEMBL8709789 | 0.91 | MEN1 (0.39) | ITGB3ITGAVPPARAMAPTMEN1 | |
| SCHEMBL8709447 | 0.88 | ITGB3 (0.48) | ITGB3ITGAVEGFRERBB2LARS1 | |
| SCHEMBL8709876 | 0.87 | BCL2 (0.42) | ITGB3ITGAVEGFRERBB2BCL2 | |
| SCHEMBL8709683 | 0.87 | ITGB3 (0.43) | ITGB3ITGAVEGFRERBB2LARS1 | |
| SCHEMBL8706743 | 0.85 | TARS1 (0.39) | ITGB3ITGAVEGFRERBB2LARS1 | |
| SCHEMBL8709162 | 0.84 | MAPT (0.45) | ITGB3ITGAVEGFRERBB2LARS1 | |
| SCHEMBL8712259 | 0.84 | BMP1 (0.43) | EGFRERBB2PPARAMAPTMEN1 | |
| SCHEMBL8706237 | 0.83 | ITGB3 (0.40) | ITGB3ITGAVMAPTPOLBHSD17B10 | |
| SCHEMBL8712032 | 0.82 | SLC7A5 (0.43) | ITGB3ITGAVMAPTMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1998041515-A1 | ENDOTHOLIN RECEPTOR ANTAGONISTS | MERCK PATENT GMBH (DE) | 1998-09-24 | — | — | WO | disclosed |