Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB3 | P05106 | 1/20 | 0.48 |
| ▸ | ITGAV | P06756 | 1/20 | 0.48 |
| ▸ | LARS1 | Q9P2J5 | 1/20 | 0.39 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.39 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | POLB | P06746 | 2/20 | 0.39 |
| ▸ | PKLR | P30613 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 5/20 | 0.38 |
| ▸ | EGFR | P00533 | 1/20 | 0.38 |
| ▸ | ERBB2 | P04626 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | PPARA | Q07869 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8709683 | 0.94 | ITGB3 (0.43) | ITGB3ITGAVLARS1PTPN1PTPN11 | |
| SCHEMBL8705691 | 0.91 | MAPT (0.50) | ITGB3ITGAVMEN1KMT2APOLB | |
| SCHEMBL8705122 | 0.90 | HTR6 (0.45) | ITGB3ITGAVMEN1KMT2APOLB | |
| SCHEMBL8709876 | 0.89 | BCL2 (0.42) | ITGB3ITGAVMEN1KMT2APOLB | |
| SCHEMBL8709162 | 0.88 | MAPT (0.45) | ITGB3ITGAVLARS1MEN1KMT2A | |
| SCHEMBL8709691 | 0.88 | ITGB3 (0.39) | ITGB3ITGAVLARS1MEN1KMT2A | |
| SCHEMBL8712032 | 0.88 | SLC7A5 (0.43) | ITGB3ITGAVMEN1KMT2AMAPT | |
| SCHEMBL8705887 | 0.86 | ITGB3 (0.53) | ITGB3ITGAVLARS1PTPN1PTPN11 | |
| SCHEMBL8711591 | 0.86 | ITGB3 (0.38) | ITGB3ITGAVLARS1MEN1KMT2A | |
| SCHEMBL8706237 | 0.86 | ITGB3 (0.40) | ITGB3ITGAVPOLBMAPTALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1998041515-A1 | ENDOTHOLIN RECEPTOR ANTAGONISTS | MERCK PATENT GMBH (DE) | 1998-09-24 | — | — | WO | disclosed |