Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB3 | P05106 | 1/20 | 0.43 |
| ▸ | ITGAV | P06756 | 1/20 | 0.43 |
| ▸ | LARS1 | Q9P2J5 | 1/20 | 0.39 |
| ▸ | PPARA | Q07869 | 3/20 | 0.37 |
| ▸ | MAPT | P10636 | 4/20 | 0.37 |
| ▸ | EGFR | P00533 | 3/20 | 0.37 |
| ▸ | ERBB2 | P04626 | 3/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 3/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | PKM | P14618 | 1/20 | 0.36 |
| ▸ | P4HTM | Q9NXG6 | 1/20 | 0.36 |
| ▸ | PKLR | P30613 | 1/20 | 0.36 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8709447 | 0.94 | ITGB3 (0.48) | ITGB3ITGAVLARS1PPARAMAPT | |
| SCHEMBL8711591 | 0.90 | ITGB3 (0.38) | ITGB3ITGAVLARS1PPARAMAPT | |
| SCHEMBL8705122 | 0.89 | HTR6 (0.45) | ITGB3ITGAVMAPTNPC1ALDH1A1 | |
| SCHEMBL8711403 | 0.89 | KDM4E (0.48) | MAPTNPC1ALDH1A1RAB9ATSHR | |
| SCHEMBL8709876 | 0.88 | BCL2 (0.42) | ITGB3ITGAVMAPTEGFRERBB2 | |
| SCHEMBL8709132 | 0.88 | EPHX2 (0.41) | ITGB3ITGAVPPARAMAPTALDH1A1 | |
| SCHEMBL8709162 | 0.87 | MAPT (0.45) | ITGB3ITGAVLARS1PPARAMAPT | |
| SCHEMBL8712032 | 0.87 | SLC7A5 (0.43) | ITGB3ITGAVMAPTALDH1A1MEN1 | |
| SCHEMBL8709691 | 0.87 | ITGB3 (0.39) | ITGB3ITGAVLARS1PPARAMAPT | |
| SCHEMBL8708878 | 0.86 | LARS1 (0.43) | ITGB3ITGAVLARS1MAPTGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1998041515-A1 | ENDOTHOLIN RECEPTOR ANTAGONISTS | MERCK PATENT GMBH (DE) | 1998-09-24 | — | — | WO | disclosed |