Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRIK1 | P39086 | 2/20 | 0.39 |
| ▸ | GRIK2 | Q13002 | 2/20 | 0.39 |
| ▸ | CPA1 | P15085 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29497160 | 0.85 | GRIK1 (0.45) | GRIK1GRIK2CPA1CYP2C19 | |
| SCHEMBL531800 | 0.84 | GRIK1 (0.42) | GRIK1GRIK2CPA1CYP2C19 | |
| SCHEMBL1741585 | 0.77 | TSHR (0.32) | — | |
| SCHEMBL8841243 | 0.75 | GRIK1 (0.32) | GRIK1GRIK2 | |
| SCHEMBL5805533 | 0.71 | CA2 (0.44) | GRIK1GRIK2CPA1 | |
| SCHEMBL360445 | 0.70 | GRIK1 (0.35) | GRIK1GRIK2CPA1CYP2C19 | |
| SCHEMBL563739 | 0.70 | — | — | |
| SCHEMBL29004325 | 0.69 | CA2 (0.46) | GRIK1GRIK2 | |
| SCHEMBL150292 | 0.69 | TSHR (0.38) | — | |
| SCHEMBL27789090 | 0.67 | TSHR (0.46) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1998054162-A1 | PREPARATION OF ALKYL 4,5-DIHYDRO-η,5-DIOXO-2-ARYL-4-OXAZOLEBUTANOATES | FINETECH LTD. (IL) | 1998-12-03 | — | — | WO | claimed |
| WO-1998054162-A1 | PREPARATION OF ALKYL 4,5-DIHYDRO-η,5-DIOXO-2-ARYL-4-OXAZOLEBUTANOATES | FINETECH LTD. (IL) | 1998-12-03 | — | — | WO | disclosed |
| WO-1998054162-A1 | PREPARATION OF ALKYL 4,5-DIHYDRO-η,5-DIOXO-2-ARYL-4-OXAZOLEBUTANOATES | FINETECH LTD. (IL) | 1998-12-03 | — | — | WO | disclosed |
| US-4943646-A | WITH N-ORGANOHYDROXAMIC ACID | MONSANTO COMPANY (US) | 1990-07-24 | — | — | US | disclosed |
| US-4939299-A | Succinyl dihydroxamic acids | MONSANTO COMPANY (US) | 1990-07-03 | — | — | US | disclosed |
| EP-0271468-A2 | Gallium complexes and solvent extraction of gallium | Monsanto Company (US) | 1988-06-15 | — | — | EP | disclosed |
| US-4741887-A | Gallium complexes and solvent extraction of gallium | MONSANTO COMPANY (US) | 1988-05-03 | — | — | US | disclosed |
| US-3966801-A | ANTIINFLAMMATORY AGENTS | WILLIAM H. RORER, INC. (US) | 1976-06-29 | — | — | US | disclosed |