SCHEMBL150292

SCHEMBL150292

CCC(CC(=O)Cl)C(=O)Cl

nearest known ligand 0.38

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
TSHR P16473 3/20 0.38
USP2 O75604 1/20 0.37
ALDH1A1 P00352 3/20 0.35
TP53 P04637 1/20 0.35
CA2 P00918 6/20 0.34
MAPK1 P28482 1/20 0.34
CA1 P00915 4/20 0.33
SLC1A3 P43003 1/20 0.33
SLC1A2 P43004 1/20 0.33
SLC1A1 P43005 1/20 0.33
KMT2A Q03164 1/20 0.31
SMN1; SMN2 Q16637 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1741585 0.83 TSHR (0.32) TSHR
SCHEMBL176693 0.83
SCHEMBL334918 0.82 CA2 (0.48) TSHRUSP2ALDH1A1TP53CA2
SCHEMBL8841243 0.80 GRIK1 (0.32) TSHR
Ammonia Solution, Strong SCHEMBL10336370 0.80
SCHEMBL28365073 0.78 TSHR (0.40) TSHRUSP2ALDH1A1TP53CA2
SCHEMBL8589382 0.77 TSHR (0.44) TSHRALDH1A1TP53CA2CA1
SCHEMBL8228378 0.77 CA1 (0.39) TSHRUSP2ALDH1A1CA2CA1
SCHEMBL27662647 0.77 CA2 (0.48) TSHRALDH1A1TP53CA2MAPK1
SCHEMBL31595979 0.76

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 680 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117866071-A Preparation method of protein iron succinate 圣嘉(滨海)生物医药科技有限公司 2024-04-12 CN claimed
CN-114773588-A DBCO modified polyethylene glycol linking agent and synthesis method thereof 武汉翱飞科技有限公司 2022-07-22 CN claimed
US-20020045751-A1 Thyromimetic organic compounds NOVARTIS AG (CH) 2002-04-18 US claimed
EP-0303279-B1 Reactive hindered amine light stabilizers ATOCHEM NORTH AMERICA ELF (US) 1996-09-25 EP claimed
EP-0410970-B1 REACTIVE HINDERED AMINE LIGHT STABILIZERS ATOCHEM NORTH AMERICA ELF (US) 1996-08-14 EP claimed
US-5214147-A Reacting piperdinyl half-ester half-amide with hydrazine; heat and light stabilizers for anhydride copolymers by chemical attachment of hydrazide functional group ELF ATOCHEM NORTH AMERICA, INC. (US) 1993-05-25 US claimed
EP-0440329-A1 S-substituted carbonyl substituted betathioacrylamide biocides and fungicides ROHM AND HAAS COMPANY (US) 1991-08-07 EP claimed
EP-0303279-A2 Reactive hindered amine light stabilizers ELF ATOCHEM NORTH AMERICA, INC. (US) 1989-02-15 EP claimed
US-4219641-A Process for preparing erythromycin succinate THE UPJOHN COMPANY (US) 1980-08-26 US claimed
JP-5001093-A None JP disclosed
CN-117720466-B 2 '-Acetyl-2', 3 '-dihydro-4'H-spiro [ cyclohexane-1, 1 '-isoquinoline ] -4' -ketone compound and preparation method and application thereof 承德医学院 2026-05-19 CN disclosed
US-12459940-B2 Oxazole compound as multi-targeted inhibitor of IRAK4 and BTK Shanghai Fosun Pharmaceutical Industrial Development Co., Ltd. (CN) 2025-11-04 US disclosed
EP-3998264-B1 OXAZOLE COMPOUND AS MULTI-TARGETED INHIBITOR OF IRAK4 AND BTK SHANGHAI FOSUN PHARMACEUTICAL IND DEVELOPMENT CO LTD (CN) 2025-08-20 EP disclosed
EP-4573086-A1 METHANOGEN INHIBITORS Agrizeronz Limited Partnership (NZ) 2025-06-25 EP disclosed
EP-0013107-A1 16-Hydroxy-16-vinyl (or cyclopropyl)-prostan-1-ols and pharmaceutical compositions containing the same AMERICAN CYANAMID COMPANY (US) 1980-07-09 EP disclosed
US-4206151-A BRONCHODILATOR, ANTISECRETORY, HYPOTENSIVE AMERICAN CYANAMID COMPANY (US) 1980-06-03 US disclosed
US-4201866-A ADRENERGIC BLOCKING AGENTS AMERICAN HOME PRODUCTS CORPORATION (US) 1980-05-06 US disclosed
US-4165365-A ANTIALLERGENS ESPECIALLY FOR ASTHMA SMITHKLINE CORPORATION (US) 1979-08-21 US disclosed
EP-0002590-A1 Novel prostaglandin compounds, processes for the preparation thereof and pharmaceutical compositions containing them AMERICAN CYANAMID COMPANY (US) 1979-06-27 EP disclosed
US-4136100-A BLUE-VIOLET TO GREEN-BLUE DYEINGS ON CELLULOSE TEXTILES BASF AKTIENGESELLSCHAFT (DE) 1979-01-23 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12459940-B2 Oxazole compound as multi-targeted inhibitor of IRAK4 and BTK IRAK4, IRAK2, IRAK3 TSHR 3616/4885USP2 1843/4885ALDH1A1 3215/4885
US-20020045751-A1 Thyromimetic organic compounds TPO, THRA, LPO TSHR 14/4885USP2 3872/4885ALDH1A1 475/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.