Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | WDR5 | P61964 | 2/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.53 |
| ▸ | TSHR | P16473 | 1/20 | 0.53 |
| ▸ | HTT | P42858 | 1/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.50 |
| ▸ | MEN1 | O00255 | 3/20 | 0.50 |
| ▸ | GAA | P10253 | 3/20 | 0.49 |
| ▸ | F10 | P00742 | 2/20 | 0.47 |
| ▸ | CSF1R | P07333 | 1/20 | 0.46 |
| ▸ | BACE1 | P56817 | 1/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8716846 | 0.86 | WDR5 (0.48) | WDR5ALDH1A1KDM4ETSHRHTT | |
| SCHEMBL8716619 | 0.84 | WDR5 (0.51) | WDR5ALDH1A1KDM4ETSHRHTT | |
| SCHEMBL8908801 | 0.81 | MAPK1 (0.57) | ALDH1A1KDM4ETSHRHTTKMT2A | |
| SCHEMBL13832429 | 0.79 | BRPF1 (0.45) | WDR5ALDH1A1KDM4EKMT2AMEN1 | |
| SCHEMBL8716632 | 0.79 | KMT2A (0.46) | WDR5ALDH1A1KMT2AMEN1GAA | |
| SCHEMBL17857107 | 0.77 | IRAK4 (0.51) | TSHRKMT2APOLB | |
| SCHEMBL19221922 | 0.76 | ABL1 (0.46) | WDR5ALDH1A1KDM4EKMT2AMEN1 | |
| SCHEMBL29823053 | 0.76 | ABL1 (0.46) | WDR5ALDH1A1KDM4EKMT2AMEN1 | |
| SCHEMBL4568017 | 0.76 | GAA (0.50) | HTTKMT2AMEN1GAAF10 | |
| SCHEMBL29991362 | 0.76 | GAA (0.60) | ALDH1A1KDM4ETSHRHTTKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1998031669-A1 | NOVEL ARYLPIPERAZINE DERIVED FROM PIPERIDINE AS ANTIDEPRESSANT MEDICINES | PIERRE FABRE MEDICAMENT (FR) | 1998-07-23 | — | — | WO | disclosed |