Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | WDR5 | P61964 | 10/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.48 |
| ▸ | GAA | P10253 | 2/20 | 0.48 |
| ▸ | SRPK1 | Q96SB4 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.44 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8716846 | 0.87 | WDR5 (0.48) | WDR5SMN1; SMN2ALDH1A1GAASRPK1 | |
| SCHEMBL8711040 | 0.84 | WDR5 (0.54) | WDR5ALDH1A1GAAMEN1TSHR | |
| SCHEMBL8908801 | 0.82 | MAPK1 (0.57) | SMN1; SMN2ALDH1A1L3MBTL1GAAMEN1 | |
| SCHEMBL8716632 | 0.80 | KMT2A (0.46) | WDR5SMN1; SMN2ALDH1A1L3MBTL1GAA | |
| SCHEMBL23606384 | 0.78 | HDAC3 (0.45) | WDR5ALDH1A1L3MBTL1GAAHTT | |
| SCHEMBL30044576 | 0.78 | HDAC3 (0.45) | WDR5ALDH1A1L3MBTL1GAAHTT | |
| SCHEMBL15614546 | 0.77 | MAPT (0.51) | SMN1; SMN2ALDH1A1MEN1MAPTTSHR | |
| SCHEMBL857284 | 0.77 | HTT (0.55) | SMN1; SMN2ALDH1A1GAAMAPTHTT | |
| SCHEMBL13864827 | 0.76 | DRD2 (0.40) | HDAC3HDAC8 | |
| SCHEMBL994653 | 0.76 | NPC1 (0.58) | SMN1; SMN2ALDH1A1L3MBTL1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1998031669-A1 | NOVEL ARYLPIPERAZINE DERIVED FROM PIPERIDINE AS ANTIDEPRESSANT MEDICINES | PIERRE FABRE MEDICAMENT (FR) | 1998-07-23 | — | — | WO | disclosed |