Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 5/20 | 0.46 |
| ▸ | MEN1 | O00255 | 4/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.46 |
| ▸ | TP53 | P04637 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | HTR1A | P08908 | 1/20 | 0.43 |
| ▸ | HTR1D | P28221 | 1/20 | 0.43 |
| ▸ | HTR1B | P28222 | 1/20 | 0.43 |
| ▸ | USP2 | O75604 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | BRPF1 | P55201 | 1/20 | 0.42 |
| ▸ | WDR5 | P61964 | 4/20 | 0.41 |
| ▸ | ABL1 | P00519 | 1/20 | 0.41 |
| ▸ | SRC | P12931 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8716846 | 0.90 | WDR5 (0.48) | KMT2AMEN1MAPK1SMN1; SMN2LMNA | |
| SCHEMBL8908801 | 0.84 | MAPK1 (0.57) | KMT2AMEN1MAPK1SMN1; SMN2LMNA | |
| SCHEMBL23606834 | 0.81 | WDR5 (0.41) | KMT2AMEN1MAPK1SMN1; SMN2LMNA | |
| SCHEMBL30044351 | 0.81 | WDR5 (0.41) | KMT2AMEN1MAPK1SMN1; SMN2LMNA | |
| SCHEMBL22765710 | 0.80 | NPC1 (0.46) | KMT2AMEN1MAPK1SMN1; SMN2LMNA | |
| SCHEMBL8716619 | 0.80 | WDR5 (0.51) | KMT2AMEN1SMN1; SMN2GAAL3MBTL1 | |
| SCHEMBL13832429 | 0.79 | BRPF1 (0.45) | KMT2AMEN1MAPK1SMN1; SMN2HTR1A | |
| SCHEMBL12466602 | 0.79 | MAPT (0.51) | KMT2AMEN1MAPK1NPSR1GAA | |
| SCHEMBL8711040 | 0.79 | WDR5 (0.54) | KMT2AMEN1GAAALDH1A1WDR5 | |
| SCHEMBL17857107 | 0.78 | IRAK4 (0.51) | KMT2AMAPK1TP53HTR1AHTR1D |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1998031669-A1 | NOVEL ARYLPIPERAZINE DERIVED FROM PIPERIDINE AS ANTIDEPRESSANT MEDICINES | PIERRE FABRE MEDICAMENT (FR) | 1998-07-23 | — | — | WO | disclosed |