Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 3/20 | 0.51 |
| ▸ | SIGMAR1 | Q99720 | 6/20 | 0.45 |
| ▸ | DRD3 | P35462 | 2/20 | 0.42 |
| ▸ | HTR7 | P34969 | 5/20 | 0.41 |
| ▸ | CARM1 | Q86X55 | 1/20 | 0.40 |
| ▸ | PRMT6 | Q96LA8 | 1/20 | 0.40 |
| ▸ | SLC18A3 | Q16572 | 2/20 | 0.40 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.40 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.40 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.40 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.40 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.40 |
| ▸ | DRD4 | P21917 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8702104 | 0.88 | SIGMAR1 (0.48) | DRD2SIGMAR1DRD3HTR7CARM1 | |
| Hydrochloric Acid SCHEMBL8702126 | 0.87 | SIGMAR1 (0.47) | DRD2SIGMAR1DRD3HTR7CARM1 | |
| Hydrochloric Acid SCHEMBL8705873 | 0.84 | HTR7 (0.40) | DRD2SIGMAR1DRD3HTR7CHRM4 | |
| SCHEMBL8705859 | 0.83 | CCR1 (0.45) | DRD2SIGMAR1HTR7 | |
| SCHEMBL8709417 | 0.80 | ALDH1A1 (0.39) | — | |
| SCHEMBL8710937 | 0.80 | ALDH1A1 (0.37) | — | |
| SCHEMBL8707825 | 0.78 | SIGMAR1 (0.50) | DRD2SIGMAR1DRD3HTR7CARM1 | |
| SCHEMBL8706332 | 0.77 | SIGMAR1 (0.48) | DRD2SIGMAR1DRD3HTR7CARM1 | |
| SCHEMBL8704596 | 0.76 | SIGMAR1 (0.47) | DRD2SIGMAR1DRD3HTR7CARM1 | |
| SCHEMBL8708829 | 0.76 | CCR1 (0.46) | DRD2SIGMAR1DRD3HTR7CHRM2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1998002432-A1 | BICYCLIC COMPOUNDS FOR CONTROLLING MICTURITION | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1998-01-22 | — | — | WO | disclosed |