Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 9/20 | 0.48 |
| ▸ | DRD2 | P14416 | 2/20 | 0.46 |
| ▸ | CARM1 | Q86X55 | 1/20 | 0.43 |
| ▸ | PRMT6 | Q96LA8 | 1/20 | 0.43 |
| ▸ | HTR7 | P34969 | 5/20 | 0.43 |
| ▸ | SLC18A3 | Q16572 | 2/20 | 0.43 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.43 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.43 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.43 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.43 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.43 |
| ▸ | DRD4 | P21917 | 1/20 | 0.43 |
| ▸ | DRD3 | P35462 | 1/20 | 0.43 |
| ▸ | HTR1A | P08908 | 1/20 | 0.42 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL8702126 | 0.99 | SIGMAR1 (0.47) | SIGMAR1DRD2CARM1PRMT6HTR7 | |
| SCHEMBL8711463 | 0.88 | DRD2 (0.51) | SIGMAR1DRD2CARM1PRMT6HTR7 | |
| Hydrochloric Acid SCHEMBL8708080 | 0.80 | CCR1 (0.47) | SIGMAR1DRD2HTR7 | |
| SCHEMBL8706332 | 0.80 | SIGMAR1 (0.48) | SIGMAR1DRD2CARM1PRMT6HTR7 | |
| SCHEMBL8707825 | 0.80 | SIGMAR1 (0.50) | SIGMAR1DRD2CARM1PRMT6HTR7 | |
| Hydrochloric Acid SCHEMBL8705873 | 0.79 | HTR7 (0.40) | SIGMAR1DRD2HTR7CHRM4DRD4 | |
| SCHEMBL8704596 | 0.79 | SIGMAR1 (0.47) | SIGMAR1DRD2CARM1PRMT6HTR7 | |
| SCHEMBL8704499 | 0.78 | OPRM1 (0.39) | — | |
| SCHEMBL8706705 | 0.78 | OPRM1 (0.39) | CHRM2 | |
| SCHEMBL8701565 | 0.76 | HTR7 (0.55) | SIGMAR1DRD2CARM1PRMT6HTR7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1998002432-A1 | BICYCLIC COMPOUNDS FOR CONTROLLING MICTURITION | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1998-01-22 | — | — | WO | disclosed |