Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR1 | P21554 | 2/20 | 0.36 |
| ▸ | CNR2 | P34972 | 2/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | GRIN1 | Q05586 | 4/20 | 0.30 |
| ▸ | GRIN2A | Q12879 | 4/20 | 0.30 |
| ▸ | GRIN2D | O15399 | 3/20 | 0.30 |
| ▸ | GRIN2C | Q14957 | 3/20 | 0.30 |
| ▸ | GRIN2B | Q13224 | 2/20 | 0.30 |
| ▸ | KIF11 | P52732 | 3/20 | 0.30 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | TTR | P02766 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8086291 | 0.91 | KIF11 (0.34) | CNR1CNR2TSHRCYP1A2GRIN1 | |
| SCHEMBL8659893 | 0.74 | TRPA1 (0.37) | TSHRCYP1A2GRIN1GRIN2AGRIN2D | |
| SCHEMBL10770500 | 0.72 | MEN1 (0.38) | CYP1A2GRIN1GRIN2AGRIN2DGRIN2C | |
| Chlorotriphenylmethane SCHEMBL461 | 0.69 | TSHR (0.65) | TSHRCYP1A2 | |
| Chlorotriphenylmethane SCHEMBL16781670 | 0.69 | TSHR (0.65) | TSHRCYP1A2 | |
| SCHEMBL8660267 | 0.69 | THRB (0.34) | CYP1A2GRIN1GRIN2AGRIN2DGRIN2C | |
| SCHEMBL3399635 | 0.69 | CPA3 (0.49) | TSHRCYP1A2KIF11 | |
| SCHEMBL914102 | 0.68 | KDM4E (0.39) | KIF11 | |
| SCHEMBL11290864 | 0.68 | KDM4E (0.33) | CNR2CYP1A2GRIN1GRIN2AGRIN2D | |
| Chlorotriphenylmethane SCHEMBL27365380 | 0.68 | TSHR (0.55) | CNR1CNR2TSHRCYP1A2KIF11 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1998007693-A1 | SYNTHESIS OF BISINDOLYLMALIMIDES | ELI LILLY AND COMPANY (US) | 1998-02-26 | — | — | WO | disclosed |