Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLAU | P00749 | 1/20 | 0.41 |
| ▸ | NNMT | P40261 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.35 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.34 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | APOBEC3A | P31941 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.33 |
| ▸ | TUBB4A | P04350 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9510455 | 0.73 | HTT (0.38) | ALDH1A1SMN1; SMN2MAPK1LMNAHTT | |
| SCHEMBL347496 | 0.72 | NNMT (0.46) | NNMTALDH1A1SMN1; SMN2MAPK1LMNA | |
| SCHEMBL8717093 | 0.70 | SMN1; SMN2 (0.51) | PLAUALDH1A1SMN1; SMN2LMNAMEN1 | |
| SCHEMBL1006528 | 0.69 | ALDH1A1 (0.38) | NNMTALDH1A1SMN1; SMN2MAPK1LMNA | |
| SCHEMBL4761854 | 0.69 | TUBB4A (0.38) | ALDH1A1SMN1; SMN2MAPK1LMNANCOA1 | |
| SCHEMBL11466514 | 0.67 | GSK3B (0.42) | NNMTALDH1A1SMN1; SMN2LMNANCOA1 | |
| SCHEMBL15573104 | 0.67 | HSD17B10 (0.46) | ALDH1A1KDM4EMEN1KMT2AMAPT | |
| SCHEMBL31012417 | 0.67 | HSD17B10 (0.46) | ALDH1A1KDM4EMEN1KMT2AMAPT | |
| SCHEMBL13729466 | 0.66 | SMN1; SMN2 (0.38) | NNMTALDH1A1SMN1; SMN2MAPK1LMNA | |
| SCHEMBL1545264 | 0.66 | MAPK1 (0.68) | PLAUMAPK1KMT2ACYP1A2TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5776963-A | ANTIPSYCHOTIC AGENTS | HOECHST MARION ROUSSEL, INC. (US) | 1998-07-07 | — | — | US | disclosed |