SCHEMBL8712153

SCHEMBL8712153

O=C(SSC(=O)c1ccc(O)cc1)c1ccc(O)cc1

nearest known ligand 0.57

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 4/20 0.57
LMNA P02545 2/20 0.57
HPGD P15428 2/20 0.57
HTT P42858 2/20 0.57
ESR1 P03372 1/20 0.57
ESR2 Q92731 1/20 0.57
PKM P14618 1/20 0.57
CA1 P00915 4/20 0.55
CA2 P00918 4/20 0.55
CA12 O43570 3/20 0.55
CA9 Q16790 3/20 0.55
CA14 Q9ULX7 3/20 0.55
CA7 P43166 2/20 0.55
CA3 P07451 2/20 0.55
TYR P14679 2/20 0.55
CA4 P22748 2/20 0.55
CA5A P35218 2/20 0.55
CA5B Q9Y2D0 2/20 0.55
DRD1 P21728 1/20 0.55
CA6 P23280 1/20 0.55

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11771370 0.79 HPGD (0.52) MAPTLMNAHPGDHTTESR1
SCHEMBL28666247 0.79 LMNA (0.46) MAPTLMNAHPGDHTTESR1
SCHEMBL8715068 0.78 TSHR (0.67) CA1CA2CA12CA9CA14
SCHEMBL1603880 0.77 MAPT (0.50) MAPTLMNAHPGDHTTESR1
SCHEMBL777846 0.76 ALDH1A1 (0.59) MAPTLMNAHPGDHTTPKM
SCHEMBL8712649 0.76 HPGD (0.58) MAPTLMNAHPGDNPC1RAB9A
SCHEMBL8718125 0.76 LMNA (0.46) MAPTLMNAHPGDHTTPKM
SCHEMBL8715024 0.76 CES2 (0.59) MAPTLMNAHPGDCA1CA2
SCHEMBL8716211 0.76 CES2 (0.59) MAPTLMNACA1CA2CES2
SCHEMBL168007 0.74 CES1 (0.55) MAPTLMNAHPGDCA1CA2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5847061-A Process for producing polymers having terminal functional group which may be protected KURARAY CO., LTD. (JP) 1998-12-08 US disclosed
EP-0704460-B1 PROCESS FOR PRODUCING POLYMER TERMINATED WITH OPTIONALLY PROTECTED FUNCTIONAL GROUP KURARAY CO (JP) 1998-11-04 EP disclosed
EP-0704460-A1 PROCESS FOR PRODUCING POLYMER TERMINATED WITH OPTIONALLY PROTECTED FUNCTIONAL GROUP KURARAY CO., LTD. (JP) 1996-04-03 EP disclosed