Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR1A | P08908 | 11/20 | 0.36 |
| ▸ | HTR1B | P28222 | 8/20 | 0.36 |
| ▸ | HTR1D | P28221 | 7/20 | 0.36 |
| ▸ | HTR2A | P28223 | 5/20 | 0.33 |
| ▸ | MPO | P05164 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | TP53 | P04637 | 1/20 | 0.31 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.31 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8715593 | 0.81 | HTR2A (0.35) | HTR1AHTR2AMPO | |
| SCHEMBL7055794 | 0.70 | — | — | |
| SCHEMBL8711894 | 0.67 | MPO (0.53) | MPO | |
| SCHEMBL8717491 | 0.65 | HTR1A (0.73) | HTR1AHTR1BHTR1DHTR2AMPO | |
| SCHEMBL8712366 | 0.63 | MPO (0.46) | MPO | |
| SCHEMBL25748617 | 0.61 | HTR1B (0.48) | HTR1AHTR1BHTR1DHTR2AKDM4E | |
| SCHEMBL8717501 | 0.61 | MPO (0.53) | MPOKDM4ETP53CYP1A2CYP2D6 | |
| SCHEMBL25747934 | 0.60 | HTR2A (0.54) | HTR1AHTR1BHTR1DHTR2AMPO | |
| SCHEMBL25747939 | 0.60 | HTR1B (0.47) | HTR1AHTR1BHTR1DHTR2AKDM4E | |
| SCHEMBL30877208 | 0.59 | HTR2A (0.61) | HTR1AHTR2AMPO |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5770610-A | ADMINISTERING R-(+)-N-(2-METHYL-2-(5-METHOXY-6-CHLOROINDOL-3-YL)ETHYL) ACETAMIDE | ELI LILLY AND COMPANY (US) | 1998-06-23 | — | — | US | disclosed |