Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2A | P28223 | 5/20 | 0.35 |
| ▸ | HTR1A | P08908 | 3/20 | 0.34 |
| ▸ | MTNR1A | P48039 | 3/20 | 0.33 |
| ▸ | MTNR1B | P49286 | 3/20 | 0.33 |
| ▸ | MPO | P05164 | 2/20 | 0.33 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.32 |
| ▸ | HTR2B | P41595 | 1/20 | 0.32 |
| ▸ | HTR6 | P50406 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8712426 | 0.81 | HTR1A (0.36) | HTR2AHTR1AMPO | |
| SCHEMBL7051623 | 0.70 | LMNA (0.31) | LMNA | |
| SCHEMBL21593329 | 0.63 | ALDH1A1 (0.38) | HTR2ALMNA | |
| SCHEMBL30877195 | 0.61 | HTR2A (0.61) | HTR2AHTR1AMTNR1AMTNR1BMPO | |
| SCHEMBL29206520 | 0.61 | HTR2A (0.61) | HTR2AHTR1AMTNR1AMTNR1BMPO | |
| SCHEMBL29206367 | 0.61 | HTR2A (0.57) | HTR2AHTR1AMPOSLC6A4 | |
| SCHEMBL8715594 | 0.60 | MEN1 (0.32) | MTNR1AMTNR1BLMNA | |
| SCHEMBL24694054 | 0.60 | HTR2A (0.52) | HTR2AHTR1AMTNR1AMTNR1BSLC6A4 | |
| SCHEMBL25748619 | 0.60 | HTR1A (0.61) | HTR2AHTR1AMTNR1AMTNR1BMPO | |
| SCHEMBL8711894 | 0.60 | MPO (0.53) | MTNR1AMTNR1BMPO |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5770610-A | ADMINISTERING R-(+)-N-(2-METHYL-2-(5-METHOXY-6-CHLOROINDOL-3-YL)ETHYL) ACETAMIDE | ELI LILLY AND COMPANY (US) | 1998-06-23 | — | — | US | disclosed |