Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 3/20 | 0.55 |
| ▸ | RAB9A | P51151 | 3/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.55 |
| ▸ | MEN1 | O00255 | 2/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.55 |
| ▸ | HCAR3 | P49019 | 1/20 | 0.50 |
| ▸ | KEAP1 | Q14145 | 2/20 | 0.48 |
| ▸ | F12 | P00748 | 1/20 | 0.47 |
| ▸ | HTT | P42858 | 2/20 | 0.47 |
| ▸ | CYP19A1 | P11511 | 3/20 | 0.46 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 3/20 | 0.46 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.46 |
| ▸ | KMO | O15229 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 3/20 | 0.44 |
| ▸ | MGAM | O43451 | 2/20 | 0.44 |
| ▸ | AMY1A | P0DUB6 | 2/20 | 0.44 |
| ▸ | GAA | P10253 | 2/20 | 0.44 |
| ▸ | SI | P14410 | 2/20 | 0.44 |
| ▸ | MGAM2 | Q2M2H8 | 2/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12349868 | 0.80 | HCAR3 (0.57) | NPC1RAB9AKDM4EMEN1KMT2A | |
| SCHEMBL1256199 | 0.80 | HCAR3 (0.76) | RAB9AMEN1KMT2AHCAR3HPGD | |
| SCHEMBL14476937 | 0.79 | KEAP1 (0.53) | NPC1RAB9AKDM4EMEN1KMT2A | |
| SCHEMBL29751355 | 0.78 | HCAR3 (0.55) | NPC1RAB9AKDM4EMEN1KMT2A | |
| Acetic Acid SCHEMBL8713683 | 0.78 | RAB9A (0.46) | NPC1RAB9AKDM4EMEN1KMT2A | |
| SCHEMBL2884485 | 0.76 | HCAR3 (0.53) | NPC1RAB9AKDM4EMEN1KMT2A | |
| SCHEMBL8884318 | 0.75 | RAB9A (0.43) | NPC1RAB9AKDM4EMEN1KMT2A | |
| SCHEMBL14092692 | 0.75 | HCAR3 (0.57) | NPC1RAB9AMEN1KMT2AHCAR3 | |
| SCHEMBL9026711 | 0.73 | CYP19A1 (0.58) | NPC1RAB9AKDM4EMEN1KMT2A | |
| SCHEMBL27541385 | 0.73 | PDE2A (0.48) | NPC1RAB9AHTTHPGDMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080194656-A1 | Benzotriazole Derivatives as Cannabinoid Receptor Antagonists | JANSSEN PHARMACEUTICA N.V. (BE) | 2008-08-14 | — | — | US | disclosed |
| US-20080194656-A1 | Benzotriazole Derivatives as Cannabinoid Receptor Antagonists | JANSSEN PHARMACEUTICA N.V. (BE) | 2008-08-14 | — | — | US | disclosed |
| US-5746840-A | Process for preparing enantiomerically pure 6-{4-chlorophenyl) (1 H-1,2,4-triazol-1-YL) methyl}-1-methyl-1 H-benzotriazole | JANSSEN PHARMACEUTICA, N.V. (BE) | 1998-05-05 | — | — | US | disclosed |
| EP-0408509-B1 | Substituted benzonitriles | CIBA GEIGY AG (CH) | 1996-03-06 | — | — | EP | disclosed |
| US-5073574-A | TETRAZOLYL SUBSTITUTED BENZONITRILES AND ANTI-TUMOR USE THEREOF | CIBA-GEIGY CORPORATION (US) | 1991-12-17 | — | — | US | disclosed |
| EP-0408509-A2 | Substituted benzonitriles | CIBA-GEIGY AG (CH) | 1991-01-16 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080194656-A1 | Benzotriazole Derivatives as Cannabinoid Receptor Antagonists | CNR1, CNR2, HTR3C | NPC1 1200/4885RAB9A 2778/4885KDM4E 3439/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.