Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.32 |
| ▸ | LMNA | P02545 | 2/20 | 0.32 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | ATG4B | Q9Y4P1 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
| ▸ | TP53 | P04637 | 1/20 | 0.30 |
| ▸ | POLB | P06746 | 1/20 | 0.30 |
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8050349 | 0.86 | MAPT (0.42) | MAPTGAASMN1; SMN2LMNAPLA2G1B | |
| SCHEMBL8032404 | 0.86 | MEN1 (0.36) | MAPTGAASMN1; SMN2LMNAHTT | |
| SCHEMBL8050920 | 0.83 | RAB9A (0.39) | MAPTGAASMN1; SMN2LMNAHTT | |
| SCHEMBL8042652 | 0.80 | KDM4E (0.40) | MAPTGAASMN1; SMN2LMNAHTT | |
| SCHEMBL8044219 | 0.77 | TSHR (0.38) | GAASMN1; SMN2LMNAHTTRAB9A | |
| SCHEMBL8044119 | 0.75 | PTGS2 (0.35) | MAPTGAASMN1; SMN2LMNAHTT | |
| SCHEMBL8047418 | 0.73 | KMT2A (0.38) | MAPTGAASMN1; SMN2RAB9AKDM4E | |
| SCHEMBL8041811 | 0.73 | ALDH1A1 (0.50) | MAPTGAASMN1; SMN2LMNAHTT | |
| SCHEMBL8033984 | 0.73 | RAB9A (0.45) | MAPTGAASMN1; SMN2LMNAHTT | |
| SCHEMBL8033836 | 0.72 | TSHR (0.47) | MAPTGAASMN1; SMN2LMNAPLA2G1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1998027092-A1 | THIAZOLE COMPOUNDS AND METHODS OF MODULATING SIGNAL TRANSDUCTION | SUGEN, INC. (US) | 1998-06-25 | — | — | WO | disclosed |