Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | XDH | P47989 | 1/20 | 0.39 |
| ▸ | SCN8A | Q9UQD0 | 2/20 | 0.37 |
| ▸ | SCN10A | Q9Y5Y9 | 2/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.36 |
| ▸ | ACACB | O00763 | 1/20 | 0.36 |
| ▸ | LCLAT1 | Q6UWP7 | 1/20 | 0.36 |
| ▸ | DHODH | Q02127 | 1/20 | 0.35 |
| ▸ | RUNX1 | Q01196 | 1/20 | 0.35 |
| ▸ | ELANE | P08246 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8710186 | 0.91 | XDH (0.39) | XDHRAB9AKDM4EALDH1A1LMNA | |
| SCHEMBL8716474 | 0.86 | SCN8A (0.39) | SCN8ASCN10ARAB9ATLR7LCLAT1 | |
| SCHEMBL8710268 | 0.83 | XDH (0.43) | XDHRAB9AMEN1KMT2AMAPT | |
| SCHEMBL8709829 | 0.76 | XDH (0.40) | XDHRAB9ADHODHLMNA | |
| SCHEMBL8710246 | 0.74 | XDH (0.40) | XDHRAB9AKDM4EALDH1A1LMNA | |
| SCHEMBL8709273 | 0.74 | XDH (0.40) | XDHRAB9AKDM4EALDH1A1MEN1 | |
| SCHEMBL8709782 | 0.73 | SLC22A12 (0.40) | XDHRAB9AMEN1LMNAKMT2A | |
| SCHEMBL8709890 | 0.69 | RAB9A (0.37) | RAB9ADHODHKDM4EALDH1A1 | |
| SCHEMBL8709054 | 0.69 | CYP3A4 (0.47) | KDM4EALDH1A1MAPT | |
| SCHEMBL8709849 | 0.69 | TLR7 (0.36) | SCN8ASCN10ATLR7DHODHRUNX1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5716971-A | FOR TREATMENT OF ANGINA PECTORIS AND HYPERTENSION | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1998-02-10 | — | — | US | disclosed |
| EP-0623597-B1 | Pyridine derivatives, with potassium channel opening activity | TAKEDA CHEMICAL INDUSTRIES LTD (JP) | 1997-10-22 | — | — | EP | disclosed |
| EP-0623597-A1 | Pyridine derivatives, with potassium channel opening activity | Takeda Chemical Industries, Ltd. (JP) | 1994-11-09 | — | — | EP | disclosed |