Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GSTP1 | P09211 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.40 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.40 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | THRB | P10828 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | PRNP | P04156 | 1/20 | 0.40 |
| ▸ | RARA | P10276 | 1/20 | 0.39 |
| ▸ | RARB | P10826 | 1/20 | 0.39 |
| ▸ | RARG | P13631 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | CYP2A6 | P11509 | 2/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.38 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2061344 | 0.85 | KDM4E (0.45) | KDM4EHTTGRIN1GRIN2AGRIN2B | |
| SCHEMBL1808153 | 0.85 | KDM4E (0.49) | KDM4EHTTALDH1A1CYP3A4THRB | |
| SCHEMBL31650634 | 0.85 | KDM4E (0.45) | KDM4EHTTGRIN1GRIN2AGRIN2B | |
| SCHEMBL4278897 | 0.82 | LMNA (0.44) | HTTGRIN1GRIN2AGRIN2BALDH1A1 | |
| SCHEMBL8437211 | 0.78 | HSP90AA1 (0.41) | GSTP1GRIN1GRIN2AGRIN2BALDH1A1 | |
| SCHEMBL8438543 | 0.76 | RARB (0.54) | CYP3A4RARARARBRARG | |
| SCHEMBL9982068 | 0.75 | GSTP1 (0.34) | GSTP1KDM4EHTTGRIN1GRIN2A | |
| SCHEMBL8310387 | 0.74 | RXRA (0.36) | RARARARBRARG | |
| SCHEMBL9982074 | 0.74 | ALDH1A1 (0.35) | GSTP1KDM4EHTTGRIN1GRIN2A | |
| SCHEMBL8438614 | 0.74 | KDM1A (0.49) | CYP2A6CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1998049136-A1 | RETINOID-LIKE COMPOUNDS | BRISTOL-MYERS SQUIBB COMPANY (US) | 1998-11-05 | — | — | WO | disclosed |