Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR1A | P08908 | 10/20 | 0.37 |
| ▸ | HTR7 | P34969 | 10/20 | 0.37 |
| ▸ | SFRP1 | Q8N474 | 3/20 | 0.37 |
| ▸ | WNT3 | P56703 | 1/20 | 0.37 |
| ▸ | CCR3 | P51677 | 1/20 | 0.36 |
| ▸ | DRD2 | P14416 | 3/20 | 0.35 |
| ▸ | HTR2A | P28223 | 1/20 | 0.35 |
| ▸ | DRD3 | P35462 | 1/20 | 0.35 |
| ▸ | ADRA1D | P25100 | 2/20 | 0.34 |
| ▸ | ADRA1A | P35348 | 2/20 | 0.34 |
| ▸ | ADRA1B | P35368 | 2/20 | 0.34 |
| ▸ | HTT | P42858 | 2/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8665585 | 0.95 | HRH2 (0.35) | HTR1AHTR7SFRP1WNT3CCR3 | |
| SCHEMBL8485533 | 0.86 | NPSR1 (0.42) | CCR3DRD2HTR2ADRD3ADRA1D | |
| SCHEMBL8713180 | 0.85 | CKS1B (0.41) | DRD2ALDH1A1 | |
| SCHEMBL8484454 | 0.84 | NPSR1 (0.42) | CCR3DRD2HTR2ADRD3ADRA1D | |
| SCHEMBL8593677 | 0.83 | ALDH1A1 (0.36) | HTR1ADRD2HTR2ADRD3HTT | |
| SCHEMBL8665880 | 0.83 | UTS2R (0.39) | DRD2 | |
| SCHEMBL8664869 | 0.82 | SMPD3 (0.38) | — | |
| SCHEMBL8717983 | 0.81 | CCR3 (0.43) | HTR1AHTR7CCR3DRD2HTT | |
| SCHEMBL8666092 | 0.81 | UTS2R (0.39) | DRD2 | |
| SCHEMBL8480390 | 0.81 | HTR1A (0.48) | HTR1AHTR7SFRP1CCR3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5739135-A | PREVENTING OR TREATING ATHEROSCLEROSIS, PANCREATITIS SECONDARY TO HYPERTRIGLYCERIDEMIA, HYPERGLYCEMIA, OBESITY | BRISTOL-MYERS SQUIBB COMPANY (US) | 1998-04-14 | — | — | US | disclosed |