Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | HPGD | P15428 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | PTGDR2 | Q9Y5Y4 | 2/20 | 0.35 |
| ▸ | CHRM2 | P08172 | 2/20 | 0.34 |
| ▸ | CHRM4 | P08173 | 2/20 | 0.34 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.34 |
| ▸ | CHRM3 | P20309 | 2/20 | 0.34 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8718493 | 0.89 | ALDH1A1 (0.42) | ALDH1A1HPGDKDM4EMAPTTDP1 | |
| SCHEMBL8717604 | 0.85 | TP53 (0.36) | ALDH1A1HPGDKDM4EMAPTTDP1 | |
| SCHEMBL8715401 | 0.82 | KMT2A (0.40) | ALDH1A1HPGDMAPTL3MBTL1HTT | |
| SCHEMBL8713402 | 0.78 | ALDH1A1 (0.36) | ALDH1A1HPGDKDM4EMAPTTDP1 | |
| SCHEMBL8715313 | 0.75 | ALDH1A1 (0.47) | ALDH1A1HPGDKDM4EMAPTL3MBTL1 | |
| SCHEMBL7346008 | 0.74 | AVPR1A (0.59) | — | |
| SCHEMBL8713944 | 0.72 | NPC1 (0.41) | ALDH1A1HPGDTP53 | |
| SCHEMBL8716877 | 0.72 | POLB (0.45) | ALDH1A1HPGDKDM4EMAPTL3MBTL1 | |
| SCHEMBL8714614 | 0.72 | MEN1 (0.52) | ALDH1A1KDM4EMAPTTP53HTT | |
| SCHEMBL8715144 | 0.71 | CFD (0.39) | TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5753677-A | Benzoheterocyclic compounds | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1998-05-19 | — | — | US | disclosed |