Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 2/20 | 0.41 |
| ▸ | RAB9A | P51151 | 2/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | ATM | Q13315 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.39 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.39 |
| ▸ | RELA | Q04206 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8715144 | 0.89 | CFD (0.39) | TP53LMNA | |
| SCHEMBL8717618 | 0.87 | KMT2A (0.41) | SMN1; SMN2HPGDKMT2APOLBTP53 | |
| SCHEMBL8718456 | 0.83 | ALDH1A1 (0.48) | NPC1RAB9ASMN1; SMN2KMT2ALMNA | |
| SCHEMBL8716877 | 0.82 | POLB (0.45) | SMN1; SMN2HPGDPOLBTP53LMNA | |
| SCHEMBL8715313 | 0.80 | ALDH1A1 (0.47) | NPC1HPGDKMT2APOLBLMNA | |
| SCHEMBL8714614 | 0.78 | MEN1 (0.52) | NPC1RAB9ASMN1; SMN2KMT2APOLB | |
| SCHEMBL8714949 | 0.77 | KMT2A (0.54) | NPC1RAB9ASMN1; SMN2HPGDKMT2A | |
| SCHEMBL8718493 | 0.77 | ALDH1A1 (0.42) | HPGDTP53LMNAALDH1A1 | |
| SCHEMBL8713003 | 0.77 | AVPR2 (0.58) | — | |
| SCHEMBL8713941 | 0.77 | POLB (0.41) | NPC1RAB9ASMN1; SMN2HPGDKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5753677-A | Benzoheterocyclic compounds | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1998-05-19 | — | — | US | disclosed |