Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 4/20 | 0.45 |
| ▸ | LMNA | P02545 | 2/20 | 0.45 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.41 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.40 |
| ▸ | MAPT | P10636 | 3/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | DRD2 | P14416 | 1/20 | 0.37 |
| ▸ | AVPR2 | P30518 | 1/20 | 0.36 |
| ▸ | AVPR1A | P37288 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 2/20 | 0.36 |
| ▸ | TAOK1 | Q7L7X3 | 1/20 | 0.36 |
| ▸ | TAOK3 | Q9H2K8 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8717618 | 0.83 | KMT2A (0.41) | POLBLMNAALDH1A1MAPTTP53 | |
| SCHEMBL8713944 | 0.82 | NPC1 (0.41) | POLBLMNAALDH1A1TP53HPGD | |
| SCHEMBL8715144 | 0.81 | CFD (0.39) | LMNATP53AVPR1A | |
| SCHEMBL8718456 | 0.78 | ALDH1A1 (0.48) | LMNAALDH1A1MAPTL3MBTL1TAOK1 | |
| SCHEMBL8715313 | 0.78 | ALDH1A1 (0.47) | POLBLMNAALDH1A1MAPTKDM4E | |
| SCHEMBL8716872 | 0.77 | POLB (0.45) | POLBLMNATAS1R3TAS1R1ALDH1A1 | |
| SCHEMBL8718493 | 0.75 | ALDH1A1 (0.42) | LMNAALDH1A1MAPTKDM4EL3MBTL1 | |
| SCHEMBL8717604 | 0.74 | TP53 (0.36) | ALDH1A1MAPTKDM4EL3MBTL1TP53 | |
| SCHEMBL8714614 | 0.74 | MEN1 (0.52) | POLBLMNAALDH1A1MAPTKDM4E | |
| SCHEMBL8713405 | 0.72 | ALDH1A1 (0.36) | ALDH1A1MAPTKDM4EL3MBTL1TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5753677-A | Benzoheterocyclic compounds | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1998-05-19 | — | — | US | disclosed |