Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.47 |
| ▸ | MAPT | P10636 | 3/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | PKM | P14618 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.42 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.42 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.42 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | AVPR2 | P30518 | 1/20 | 0.41 |
| ▸ | OXTR | P30559 | 1/20 | 0.41 |
| ▸ | AVPR1A | P37288 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | ESR1 | P03372 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8713944 | 0.80 | NPC1 (0.41) | ALDH1A1POLBLMNANPC1HPGD | |
| SCHEMBL8718493 | 0.78 | ALDH1A1 (0.42) | ALDH1A1KDM4EMAPTL3MBTL1LMNA | |
| SCHEMBL8716877 | 0.78 | POLB (0.45) | ALDH1A1KDM4EMAPTPOLBL3MBTL1 | |
| SCHEMBL8714614 | 0.77 | MEN1 (0.52) | ALDH1A1KDM4EMAPTPOLBLMNA | |
| SCHEMBL8715144 | 0.76 | CFD (0.39) | LMNAAVPR1A | |
| SCHEMBL8717604 | 0.75 | TP53 (0.36) | ALDH1A1KDM4EMAPTL3MBTL1CHRM2 | |
| SCHEMBL8713405 | 0.75 | ALDH1A1 (0.36) | ALDH1A1KDM4EMAPTL3MBTL1CHRM2 | |
| SCHEMBL8717618 | 0.75 | KMT2A (0.41) | ALDH1A1MAPTPOLBLMNAHPGD | |
| SCHEMBL8718127 | 0.75 | TAOK1 (0.54) | ALDH1A1KDM4EMAPTPOLBL3MBTL1 | |
| SCHEMBL8714949 | 0.75 | KMT2A (0.54) | ALDH1A1MAPTL3MBTL1LMNANPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5753677-A | Benzoheterocyclic compounds | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1998-05-19 | — | — | US | disclosed |