Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP13 | P45452 | 6/20 | 0.43 |
| ▸ | MMP1 | P03956 | 5/20 | 0.43 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.43 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 2/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
| ▸ | PKM | P14618 | 2/20 | 0.42 |
| ▸ | MMP9 | P14780 | 3/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | MMP2 | P08253 | 2/20 | 0.41 |
| ▸ | CA1 | P00915 | 1/20 | 0.41 |
| ▸ | CA2 | P00918 | 1/20 | 0.41 |
| ▸ | MMP8 | P22894 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.40 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.40 |
| ▸ | STS | P08842 | 1/20 | 0.40 |
| ▸ | MMP3 | P08254 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9755713 | 0.88 | ALDH1A1 (0.46) | MMP13MMP1CHRM2CHRM1HTT | |
| SCHEMBL28114919 | 0.85 | ALDH1A1 (0.41) | NPSR1LMNATSHRSMN1; SMN2GAA | |
| SCHEMBL27585806 | 0.84 | LMNA (0.47) | HTTLMNASMN1; SMN2GAA | |
| SCHEMBL28013660 | 0.79 | MAPT (0.49) | CHRM1TSHRCA1CA2STS | |
| SCHEMBL12827982 | 0.77 | PKM (0.52) | MMP13MMP1HTTNPSR1PKM | |
| SCHEMBL9755721 | 0.74 | ALDH1A1 (0.50) | HTTNPSR1LMNATSHRSMN1; SMN2 | |
| SCHEMBL28111593 | 0.74 | HTT (0.49) | HTTLMNASMN1; SMN2GAA | |
| SCHEMBL14493233 | 0.73 | TSHR (0.50) | LMNATSHRSMN1; SMN2STS | |
| SCHEMBL27731552 | 0.72 | HDAC3 (0.49) | HTTLMNATSHRSMN1; SMN2CA1 | |
| SCHEMBL9755727 | 0.72 | MEN1 (0.58) | HTTNPSR1LMNATSHRSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5847153-A | β-sulfonyl hydroxamic acids | PHARMACIA & UPJOHN COMPANY (US) | 1998-12-08 | — | — | US | disclosed |