Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 4/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | HDAC1 | Q13547 | 5/20 | 0.34 |
| ▸ | HDAC6 | Q9UBN7 | 5/20 | 0.34 |
| ▸ | HDAC4 | P56524 | 2/20 | 0.34 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.33 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.33 |
| ▸ | POLA1 | P09884 | 1/20 | 0.33 |
| ▸ | POLG | P54098 | 1/20 | 0.33 |
| ▸ | FAP | Q12884 | 1/20 | 0.33 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.33 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.33 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.33 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.33 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.33 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.33 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.33 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8709228 | 0.83 | HSP90AB1 (0.47) | HDAC1HDAC6HDAC4HSP90AA1HSP90AB1 | |
| SCHEMBL8713510 | 0.82 | MEN1 (0.41) | ACHEMEN1TSHRKMT2AHDAC1 | |
| SCHEMBL9366802 | 0.78 | MEN1 (0.63) | ACHEMEN1TSHRKMT2AHDAC1 | |
| SCHEMBL8711549 | 0.76 | ACHE (0.40) | ACHEMEN1TSHRKMT2AHDAC1 | |
| SCHEMBL9575539 | 0.76 | MEN1 (0.48) | ACHEMEN1TSHRKMT2AHDAC1 | |
| SCHEMBL8713036 | 0.75 | ACHE (0.47) | ACHEMEN1TSHRKMT2AHDAC1 | |
| SCHEMBL8896639 | 0.73 | ACHE (0.44) | ACHEMEN1TSHRKMT2AHDAC1 | |
| SCHEMBL10405793 | 0.72 | ACHE (0.44) | ACHEMEN1TSHRKMT2AHDAC1 | |
| SCHEMBL9575550 | 0.72 | ACHE (0.42) | ACHEMEN1TSHRKMT2AHDAC1 | |
| SCHEMBL8711561 | 0.72 | ACHE (0.39) | ACHEMEN1TSHRKMT2AHDAC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5726174-A | VIRICIDES, ANTITUMOR AGENTS | INSTITUTE OF ORGANIC CHEMISTRY AND BIOCHEMISTRY OF THE ACADEMY OF SCIENCES OF THE CZECH REPUBLIC (CZ) | 1998-03-10 | — | — | US | disclosed |