Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | ACHE | P22303 | 4/20 | 0.40 |
| ▸ | HDAC1 | Q13547 | 3/20 | 0.35 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.35 |
| ▸ | P2RY1 | P47900 | 3/20 | 0.34 |
| ▸ | HDAC4 | P56524 | 2/20 | 0.34 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.34 |
| ▸ | PNP | P00491 | 1/20 | 0.34 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.34 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.34 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.34 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.34 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.34 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.34 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.34 |
| ▸ | HPRT1 | P00492 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8709241 | 0.84 | HSP90AB1 (0.43) | HDAC1HDAC2HDAC4HDAC6PNP | |
| SCHEMBL8713496 | 0.82 | ACHE (0.40) | MEN1TSHRKMT2AACHEHDAC1 | |
| SCHEMBL9366802 | 0.77 | MEN1 (0.63) | MEN1TSHRKMT2AACHEHDAC1 | |
| SCHEMBL8711561 | 0.77 | ACHE (0.39) | MEN1TSHRKMT2AACHEHDAC1 | |
| SCHEMBL9575539 | 0.75 | MEN1 (0.48) | MEN1TSHRKMT2AACHEHDAC1 | |
| SCHEMBL8713036 | 0.74 | ACHE (0.47) | MEN1TSHRKMT2AACHEHDAC1 | |
| SCHEMBL8896639 | 0.72 | ACHE (0.44) | MEN1TSHRKMT2AACHEHDAC1 | |
| SCHEMBL8711549 | 0.72 | ACHE (0.40) | MEN1TSHRKMT2AACHEHDAC1 | |
| SCHEMBL8709090 | 0.72 | ENPP1 (0.56) | — | |
| SCHEMBL10405793 | 0.71 | ACHE (0.44) | MEN1TSHRKMT2AACHEHDAC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5726174-A | VIRICIDES, ANTITUMOR AGENTS | INSTITUTE OF ORGANIC CHEMISTRY AND BIOCHEMISTRY OF THE ACADEMY OF SCIENCES OF THE CZECH REPUBLIC (CZ) | 1998-03-10 | — | — | US | disclosed |